Publication	Data		Fish	Anatomy
Jones et al., 2022	FIGURE 2		ext2tw25e/tw25e	heart edematous, abnormal inner ear decreased width, abnormal lapillus decreased area, abnormal mandibular arch skeleton malformed, abnormal otic epithelium protruding, abnormal pectoral fin bud agenesis, abnormal pillar of the semicircular canal closure incomplete, abnormal sagitta decreased area, abnormal semicircular canal fusion decreased process quality, abnormal
	FIGURE 3		ext2tw25e/tw25e	brain chsy1 expression decreased amount, abnormal dorsal hyoid arch periderm vcanb expression decreased amount, abnormal otic vesicle protrusion chsy1 expression increased amount, abnormal otic vesicle protrusion vcanb expression decreased amount, abnormal otic vesicle protrusion vcanb expression increased amount, abnormal pillar of the anterior semicircular canal vcanb expression increased amount, abnormal pillar of the posterior semicircular canal vcanb expression increased amount, abnormal pleuroperitoneal region chsy1 expression absent, abnormal
	FIGURE 4		ext2tw25e/tw25e	otic vesicle anterior region ab-cs-56 labeling absent, abnormal otic vesicle posterior protrusion ab-cs-56 labeling absent, abnormal otic vesicle posterior protrusion ab-cs-56 labeling increased amount, abnormal semicircular canal fusion decreased process quality, abnormal semicircular canal morphogenesis delayed, abnormal
	FIGURE 5		ext2tw25e/tw25e	sagitta detached from macula saccule, abnormal
	FIGURE 6		ext2tw25e/tw25e	anterior crista otog expression decreased amount, abnormal anterior macula otog expression decreased amount, abnormal anterior macula otomp expression decreased amount, abnormal lateral crista otog expression decreased amount, abnormal posterior crista otog expression decreased amount, abnormal posterior macula otog expression absent, abnormal posterior macula otomp expression decreased amount, abnormal posterior macula stm expression decreased amount, abnormal
Khalil et al., 2019	Fig. 1		ext2to273b/to273b	mandibular arch skeleton morphology, abnormal mandibular arch skeleton protruding, abnormal pericardium edematous, abnormal swim bladder uninflated, abnormal whole organism curved, abnormal whole organism lacks all parts of type pectoral fin, abnormal
	Fig. 2		ext2to273b/to273b	glomerular basement membrane morphology, abnormal
Di Donato et al., 2018	Fig. 4		ext2to273b/to273b	tectal neuropile reln expression decreased amount, abnormal
Volpi et al., 2017	Fig. 3		ext2to273b/to273b ,   ext2to273b/to273b; la6Tg	pectoral fin decreased size, abnormal thymus decreased volume, abnormal thymus development disrupted, abnormal
Venero Galanternik et al., 2015	Fig. 1		ext2to79c/to79c; zf106Tg	neuromast decreased distance neuromast, abnormal posterior lateral line neuromast deposition decreased rate, abnormal posterior lateral line neuromast primordium migration arrested, abnormal posterior lateral line primordium morphology, abnormal
	Fig. 6		ext2to79c/to79c; zf106Tg	myoseptum anatomical region cxcl12a expression increased distribution, abnormal posterior lateral line neuromast primordium migration process quality, abnormal posterior lateral line primordium has extra parts of type posterior lateral line primordium filopodium, abnormal
Wiweger et al., 2014	Fig. 2		ext2to273b/to273b	ossification process quality, abnormal
	Fig. 3		ext2to273b/to273b	adductor hyohyoid increased width, abnormal adductor hyohyoid shortened, abnormal adductor mandibulae increased width, abnormal adductor mandibulae shortened, abnormal adductor operculi increased width, abnormal adductor operculi shortened, abnormal cranial cartilage shape, abnormal dilatator operculi increased width, abnormal dilatator operculi shortened, abnormal head muscle increased width, abnormal head muscle shortened, abnormal heart anatomical region has extra parts of type muscle, abnormal hyohyoideus absent, abnormal interhyoideus increased width, abnormal interhyoideus shortened, abnormal levator arcus palatini increased width, abnormal levator arcus palatini shortened, abnormal sternohyoid increased width, abnormal sternohyoid shortened, abnormal ventral intermandibularis anterior increased width, abnormal ventral intermandibularis anterior shortened, abnormal ventral intermandibularis posterior increased width, abnormal ventral intermandibularis posterior shortened, abnormal
	Fig. 4		ext2to273b/to273b	adipose tissue development premature, abnormal
	Fig. 5		ext2to273b/to273b	ossification process quality, abnormal
Holmborn et al., 2012	Fig. 10		ext2tw25e/tw25e; y1Tg	ceratohyal cartilage decreased length, abnormal Meckel's cartilage anterior side decreased distance ceratohyal cartilage posterior side, abnormal Meckel's cartilage decreased length, abnormal pharyngeal arch cartilage chondrocyte circular, abnormal pharyngeal arch cartilage chondrocyte disorganized, abnormal
	Fig. 2		ext2tw25e/tw25e; y1Tg	mandibular arch skeleton condensed, abnormal pectoral fin aplastic, abnormal pharyngeal arch cartilage chondrocyte circular, abnormal pharyngeal arch cartilage chondrocyte disorganized, abnormal pharyngeal arch cartilage decreased length, abnormal pharyngeal arch cartilage increased thickness, abnormal pharyngeal arch cartilage oriented, abnormal
	Fig. 3		ext2tw25e/tw25e; y1Tg	heparan sulfate proteoglycan biosynthetic process decreased occurrence, abnormal
	Fig. 7		ext2tw25e/tw25e; y1Tg	heparan sulfate proteoglycan biosynthetic process process quality, abnormal sulfation increased occurrence, abnormal
Wang et al., 2012	Fig. 5		ext2to273b/to273b; la203Tg; zf154Tg	Rohon-Beard neuron axon mislocalized adaxially, abnormal Rohon-Beard neuron axon subdermal, abnormal sensory neuron axon guidance disrupted, abnormal
Wiweger et al., 2012	Fig. 1		ext2to273b/to273b	ceratobranchial 5 bone has fewer parts of type ceratobranchial 5 tooth, abnormal ceratobranchial 5 tooth decreased length, abnormal ceratobranchial 5 tooth increased width, abnormal ceratobranchial 5 tooth mislocalised posteriorly, abnormal ceratobranchial 5 tooth ossified, abnormal
	Fig. 2		ext2to273b/to273b	ceratobranchial 5 bone has fewer parts of type ceratobranchial 5 tooth, abnormal
	Fig. 3		ext2to273b/to273b	ossification delayed, abnormal tooth mineralization delayed, abnormal
	Fig. 4		ext2to273b/to273b	ceratobranchial 5 bone decreased length, abnormal ceratobranchial 5 bone has fewer parts of type ceratobranchial 5 tooth, abnormal ceratobranchial 5 tooth decreased length, abnormal ceratobranchial 5 tooth increased thickness, abnormal
	Fig. 6		ext2to273b/+	ceratobranchial 5 tooth increased distance ceratobranchial 5 tooth, abnormal dorsal tooth row has fewer parts of type ceratobranchial 5 tooth, abnormal ventral tooth row has extra parts of type ceratobranchial 5 tooth, abnormal
	Fig. 7		ext2to273b/+	ceratobranchial 5 tooth decreased concentration enameloid, abnormal ceratobranchial 5 tooth distal surface split, abnormal
	Fig. S2		ext2to273b/to273b	ceratobranchial 5 bone ossified, abnormal ceratobranchial 5 tooth ossified, abnormal ossification delayed, abnormal tooth mineralization delayed, abnormal
	Fig. S3		ext2to273b/to273b	pharyngeal epithelium decreased thickness, abnormal
	Fig. S8		ext2to273b/to273b	ceratobranchial 5 bone apoptotic, abnormal
de Andrea et al., 2011	Fig. 3		ext2to273b/to273b	cranial cartilage extracellular matrix composition, abnormal cranial cartilage poly(ethylene imine) spatial pattern, abnormal
	Fig. 4		ext2to273b/to273b	cranial cartilage extracellular matrix composition, abnormal cranial cartilage poly(ethylene imine) spatial pattern, abnormal
Wiweger et al., 2011	Fig. 1		ext2to273b/to273b	glycosaminoglycan metabolic process disrupted, abnormal
	Fig. 3		ext2to273b/to273b	ceratohyal cartilage chondrocyte disorganized, abnormal chondrocyte circular, abnormal chondrocyte intercalation involved in growth plate cartilage morphogenesis arrested, abnormal
	Fig. 4		ext2to273b/to273b	cranial cartilage extracellular matrix composition, abnormal
	Fig. Table 2		ext2to273b/to273b	cranial cartilage deformed, abnormal ossification decreased occurrence, abnormal whole organism anterior-posterior axis decreased length, abnormal
	text only		ext2to273b/to273b	ceratobranchial 5 bone malformed, abnormal cleithrum decreased size, abnormal cleithrum malformed, abnormal dermal bone hypoplastic, abnormal opercle decreased size, abnormal opercle malformed, abnormal
Clément et al., 2008	Fig. 1		ext2to273b/to273b	cartilage development disrupted, abnormal cartilage element decreased length, abnormal cartilage element increased thickness, abnormal chondrocyte morphology, abnormal
	Fig. 5		ext2to273b/to273b	skeletal system development disrupted, abnormal
	Fig. 6		ext2to273b/to273b	cartilage development disrupted, abnormal chondrocyte morphology, abnormal
	text only		ext2to273b/to273b	ceratobranchial 4 cartilage decreased size, abnormal Meckel's cartilage increased size, abnormal
Phenotype Annotation (1994-2006)	Fig. for (tf205)		ext2tf205/tf205	fin decreased size, abnormal inner ear quality, abnormal mouth quality, abnormal nervous system quality, abnormal pectoral fin quality, abnormal pharyngeal arch 3-7 skeleton quality, abnormal retinal ganglion cell axon guidance quality, abnormal sensory system quality, abnormal surface structure quality, abnormal whole organism lethal (sensu genetics), abnormal
	Fig. for (to273b)		ext2to273b/to273b	fin decreased size, abnormal inner ear quality, abnormal mouth quality, abnormal nervous system quality, abnormal pectoral fin quality, abnormal pharyngeal arch 3-7 skeleton quality, abnormal retinal ganglion cell axon guidance quality, abnormal sensory system quality, abnormal surface structure quality, abnormal whole organism lethal (sensu genetics), abnormal
	Fig. for (to79c)		ext2to79c/to79c	fin decreased size, abnormal inner ear quality, abnormal mouth quality, abnormal nervous system quality, abnormal pectoral fin quality, abnormal pharyngeal arch 3-7 skeleton quality, abnormal retinal ganglion cell axon guidance quality, abnormal sensory system quality, abnormal surface structure quality, abnormal whole organism lethal (sensu genetics), abnormal
	Fig. for (tw25e)		ext2tw25e/tw25e	fin decreased size, abnormal inner ear quality, abnormal mouth quality, abnormal nervous system quality, abnormal pectoral fin quality, abnormal pharyngeal arch 3-7 skeleton quality, abnormal retinal ganglion cell axon guidance quality, abnormal sensory system quality, abnormal surface structure quality, abnormal whole organism lethal (sensu genetics), abnormal
Lee et al., 2004	Fig. 5		ext2to273b/to273b	retinal ganglion cell axon guidance disrupted, abnormal retinal ganglion cell axon irregular spatial pattern, abnormal
Begemann et al., 2000	Fig. 3		ext2tw25e/tw25e	pectoral fin absent, abnormal pectoral fin development arrested, abnormal
Grandel et al., 2000	Fig. 1		ext2to273b/to273b ,   ext2tw25e/tw25e	apical ectodermal ridge pectoral fin bud aplastic, abnormal fin fold pectoral fin bud absent, abnormal pectoral fin aplastic, abnormal pectoral fin bud hypoplastic, abnormal pectoral fin endoskeletal disc absent, abnormal pectoral girdle decreased size, abnormal
	text only		ext2to273b/to273b ,   ext2tw25e/tw25e	whole organism dead, abnormal
Karlstrom et al., 1996	Table 1		ext2to273b/to273b ,   ext2tw25e/tw25e ,   ext2tf205/tf205	optic tract structure, abnormal retinal ganglion cell axon guidance process quality, abnormal retinal ganglion cell axon misrouted, abnormal
Schilling et al., 1996	Fig. 2		ext2tw25e/tw25e	mandibular arch skeleton mislocalised posteriorly, abnormal pharyngeal arch 3-7 decreased length, abnormal pharyngeal arch 3-7 decreased size, abnormal pharyngeal arch 3-7 increased width, abnormal
	Fig. 3		ext2tw25e/tw25e	Meckel's cartilage sloped downward, abnormal pharyngeal arch 3-7 skeleton decreased size, abnormal
	Fig. 4		ext2tw25e/tw25e	mandibular arch skeleton decreased length, abnormal mandibular arch skeleton increased width, abnormal pharyngeal arch 2 skeleton decreased length, abnormal pharyngeal arch 2 skeleton increased width, abnormal pharyngeal arch 3-7 skeleton decreased length, abnormal pharyngeal arch 3-7 skeleton increased width, abnormal
	Fig. 5		ext2tw25e/tw25e	neurocranium decreased length, abnormal neurocranium increased thickness, abnormal
	Fig. Table 3		ext2to273b/to273b ,   ext2to79c/to79c ,   ext2tw25e/tw25e ,   ext2tf205/tf205	mandibular arch skeleton decreased length, abnormal mandibular arch skeleton increased thickness, abnormal pectoral fin absent, abnormal pharyngeal arch 2 skeleton decreased length, abnormal pharyngeal arch 2 skeleton increased thickness, abnormal pharyngeal arch 3-7 skeleton decreased length, abnormal pharyngeal arch 3-7 skeleton increased thickness, abnormal post-vent region curved dorsal, abnormal
	Fig. Table 4		ext2to273b/to273b ,   ext2to79c/to79c ,   ext2tw25e/tw25e ,   ext2tf205/tf205	mandibular arch skeleton decreased size, abnormal pharyngeal arch 2 skeleton decreased size, abnormal pharyngeal arch 3-7 skeleton decreased size, abnormal
Trowe et al., 1996	Fig. 4		ext2to273b/to273b	dorsomedial optic tract composition, abnormal retinal ganglion cell axon branched, abnormal retinal ganglion cell axon displaced, abnormal retinal ganglion cell axon fasciculation, abnormal retinal ganglion cell axon guidance process quality, abnormal retinal ganglion cell axon organization quality, abnormal
	Table 1		ext2to273b/to273b ,   ext2tw25e/tw25e ,   ext2tf205/tf205	dorsomedial optic tract composition, abnormal forebrain decreased size, abnormal mandibular arch skeleton morphology, abnormal olfactory placode hypoplastic, abnormal pectoral fin aplastic, abnormal pharyngeal arch 2 skeleton decreased size, abnormal pharyngeal arch 3-7 skeleton decreased size, abnormal retinal ganglion cell axon branched, abnormal retinal ganglion cell axon displaced, abnormal retinal ganglion cell axon fasciculation, abnormal retinal ganglion cell axon guidance process quality, abnormal retinal ganglion cell axon organization quality, abnormal
van Eeden et al., 1996	Fig. 3		ext2tw25e/tw25e	pectoral fin decreased length, abnormal
	Table 1		ext2to273b/to273b ,   ext2to79c/to79c ,   ext2tw25e/tw25e ,   ext2tf205/tf205	inner ear morphology, abnormal mandibular arch skeleton morphology, abnormal pectoral fin decreased size, abnormal
	Table 2		ext2to273b/to273b ,   ext2to79c/to79c ,   ext2tw25e/tw25e ,   ext2tf205/tf205	pectoral fin decreased size, abnormal
	text only		ext2to273b/to273b ,   ext2to79c/to79c ,   ext2tw25e/tw25e ,   ext2tf205/tf205	pectoral fin development disrupted, abnormal pectoral fin fold aplastic, abnormal retinal ganglion cell axon guidance process quality, abnormal whole organism viability, abnormal
Whitfield et al., 1996	Table 3		ext2to273b/to273b ,   ext2to79c/to79c ,   ext2tw25e/tw25e ,   ext2tf205/tf205	inner ear increased size, abnormal inner ear structure, abnormal