ZFIN Figure: van Eeden et al., 1996, text only

ZFIN ID: ZDB-FIG-091116-9

ZFIN ID: ZDB-FIG-091116-9

van Eeden et al., 1996 - Genetic analysis of fin formation in the zebrafish, Danio rerio. Development (Cambridge, England) 123:255-262 Full text @ Development

ADDITIONAL FIGURES

PHENOTYPE:

Fish:	bmp1a^tf5/tf5 bmp1a^th42/th42 bmp1a^{tm317a/tm317a} bmp1a^tp34/tp34 bmp1a^tp207/tp207 bmp1a^ty69/ty69 bmp1a^tz252/tz252 bmp2b^ta72a/ta72a bmp2b^{tc300a/tc300a} bob^{tu255a/tu255a} chrd^tm84/tm84 chrd^tt250/tt250 col1a1a^tt281/tt281 ddf^ta50/ta50 ddf^tc289/tc289 ddf^ti251/ti251 ddf^tj6/tj6 ext2^tf205/tf205 ext2^to79c/to79c ext2^{to273b/to273b} ext2^tw25e/tw25e extl3^te242/te242 extl3^{tg308c/tg308c} extl3^tm4/tm4 extl3^tm70g/tm70g extl3^{tm317c/tm317c} extl3^to232/to232 extl3^tp67z/tp67z extl3^tw24/tw24 fras1^{te262d/te262d} fras1^tj16/tj16 fras1^tm95b/tm95b fras1^tr274/tr274 frem1a^{tb233b/tb233b} frem1a^tc228/tc228 frem1a^{tc280b/tc280b} frem1a^te217/te217 frem1a^{te370b/te370b} frem1a^{tg308b/tg308b} frem1a^{tm235b/tm235b} frem1a^tp66/tp66 frem1a^{tq266c/tq266c} frem1a^tr240/tr240 frem1a^tz245/tz245 frem2a^ta90/ta90 ham^{te296c/te296c} ham^to16/to16 hen^{tq251f/tq251f} hen^{tt209b/tt209b} hen^tu248/tu248 hhip^{tc256d/tc256d} hmcn1^ta84/ta84 hmcn1^tb22/tb22 hmcn1^tc8/tc8 hmcn1^te335/te335 hmcn1^{tg254b/tg254b} hmcn1^{tj258a/tj258a} hmcn1^tl28b/tl28b hmcn1^{tl246a/tl246a} hmcn1^tm42b/tm42b hmcn1^tm51/tm51 hmcn1^tm68/tm68 hmcn1^{tm147c/tm147c} hmcn1^tn3/tn3 hmcn1^tn210/tn210 hmcn1^tp41a/tp41a hmcn1^tq207/tq207 hmcn1^tq274/tq274 hmcn1^tr3/tr3 hmcn1^tt231/tt231 hmcn1^tu27a/tu27a hmcn1^{tw234b/tw234b} hmcn1^ty58/ty58 hmcn1^{ty124b/ty124b} itga3b^tj2b/tj2b krm^{tc227d/tc227d} lama5^tc17/tc17 lama5^{tk219a/tk219a} lama5^tm55/tm55 llgl2^to6/to6 myo5b^tk34a/tk34a myo5b^tk38/tk38 myo5b^tt221/tt221 pek^td14/td14 prdm1a^tp39/tp39 ptch1^tj222/tj222 ptch1^tq236/tq236 smad5^ta206/ta206 smad5^{tc227a/tc227a} smad5^tx223/tx223 sox9a^tw37/tw37 sto^td11/td11 sufu^{tm146d/tm146d} szl^tm305/tm305 szl^tz209/tz209 tll1^{tc263a/tc263a} tll1^{tf215a/tf215a} tll1^{tm124a/tm124a} tll1^{tn217b/tn217b} tll1^{tt203a/tt203a} tll1^tv9b/tv9b tll1^{ty130a/ty130a} trim33^{tb222b/tb222b} trim33^{tc239b/tc239b} trim33^{tc246b/tc246b} trim33^te345/te345 trim33^tg234/tg234 trim33^{tu244b/tu244b} trim33^ty57/ty57 trim33^tz276/tz276 tut^tg30/tg30 kcnk5b^ty86d/+ lof^dt2/+ smad5^dti216c/+ smad5^dty40/+ frem2a^ta90
Observed In:	anal fin axis caudal fin caudal vein plexus fin gastrulation with mouth forming second hindbrain integument integument cell lepidotrichium median fin fold median fin fold cell median fin fold epidermis median fin fold epithelium musculoskeletal movement pectoral fin pectoral fin cell pectoral fin epithelium pectoral fin development pectoral fin fold pectoral fin fold distal region pectoral fin lepidotrichium pelvic fin lepidotrichium pharyngeal arch 2 skeleton pharyngeal arch 3-7 pharyngeal arch 3-7 skeleton post-vent region retinal ganglion cell axon guidance somite trunk musculature ventral fin fold ventral fin fold epithelium whole organism
Stage Range:	Bud to Adult

Unillustrated author statements

Gene Expression Details No data available

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
bmp1a^tf5/tf5	standard conditions	26+ somites - Day 5	median fin fold decreased length, abnormal
		Adult	fin decreased length, abnormal
bmp1a^th42/th42	standard conditions	26+ somites - Day 5	median fin fold decreased length, abnormal
		Adult	fin decreased length, abnormal
bmp1a^{tm317a/tm317a}	standard conditions	26+ somites - Day 5	median fin fold decreased length, abnormal
		Adult	fin decreased length, abnormal
bmp1a^tp207/tp207	standard conditions	26+ somites - Day 5	ventral fin fold decreased length, abnormal
		Adult	fin decreased length, abnormal
bmp1a^tp34/tp34	standard conditions	26+ somites - Day 5	ventral fin fold decreased length, abnormal
		Adult	fin decreased length, abnormal
bmp1a^ty69/ty69	standard conditions	26+ somites - Day 5	median fin fold decreased length, abnormal
		Adult	fin decreased length, abnormal
bmp1a^tz252/tz252	standard conditions	26+ somites - Day 5	median fin fold decreased length, abnormal
		Adult	fin decreased length, abnormal
bmp2b^ta72a/ta72a	standard conditions	26+ somites - Day 5	ventral fin fold hypoplastic, abnormal
bmp2b^{tc300a/tc300a}	standard conditions	26+ somites - Day 5	ventral fin fold hypoplastic, abnormal
bob^{tu255a/tu255a}	standard conditions	Pec-fin	whole organism dead, abnormal
chrd^tm84/tm84	standard conditions	26+ somites - Day 5	ventral fin fold multiple, abnormal
chrd^tt250/tt250	standard conditions	26+ somites - Day 5	ventral fin fold multiple, abnormal
col1a1a^tt281/tt281	standard conditions	26+ somites - Day 5	median fin fold decreased length, abnormal
ddf^ta50/ta50	standard conditions	Prim-5	integument cell circular, abnormal
		Protruding-mouth	axis curved, abnormal
ddf^tc289/tc289	standard conditions	Prim-5	hindbrain morphology, abnormal
		Prim-5	integument cell circular, abnormal
		Prim-5	integument necrotic, abnormal
		Protruding-mouth	axis curved, abnormal
		Protruding-mouth	fin necrotic, abnormal
ddf^ti251/ti251	standard conditions	Prim-5	integument cell circular, abnormal
		Protruding-mouth	axis curved, abnormal
		Protruding-mouth	fin necrotic, abnormal
		Protruding-mouth	hindbrain morphology, abnormal
		Protruding-mouth	integument necrotic, abnormal
ddf^tj6/tj6	standard conditions	Prim-5	integument cell circular, abnormal
		Protruding-mouth	axis curved, abnormal
		Protruding-mouth	fin necrotic, abnormal
		Protruding-mouth	hindbrain morphology, abnormal
ext2^tf205/tf205	standard conditions	Pec-fin	pectoral fin development disrupted, abnormal
		Pec-fin	whole organism viability, abnormal
		Day 5	pectoral fin fold aplastic, abnormal
		Day 5	whole organism viability, abnormal
ext2^{to273b/to273b}	standard conditions	Pec-fin	pectoral fin development disrupted, abnormal
		Day 5	pectoral fin fold aplastic, abnormal
ext2^to79c/to79c	standard conditions	Pec-fin	pectoral fin development disrupted, abnormal
		Pec-fin	retinal ganglion cell axon guidance process quality, abnormal
		Pec-fin	whole organism viability, abnormal
ext2^tw25e/tw25e	standard conditions	Pec-fin	pectoral fin development disrupted, abnormal
		Day 5	pectoral fin fold aplastic, abnormal
extl3^te242/te242	standard conditions	Protruding-mouth	pectoral fin cell circular, abnormal
		Protruding-mouth	pectoral fin fold aplastic, abnormal
		Protruding-mouth	pectoral fin fold distal region aplastic, abnormal
extl3^{tg308c/tg308c}	standard conditions	Protruding-mouth	pectoral fin cell circular, abnormal
		Protruding-mouth	pectoral fin fold aplastic, abnormal
		Protruding-mouth	pectoral fin fold distal region aplastic, abnormal
extl3^{tm317c/tm317c}	standard conditions	Protruding-mouth	pectoral fin cell circular, abnormal
		Protruding-mouth	pectoral fin fold aplastic, abnormal
		Protruding-mouth	pectoral fin fold distal region aplastic, abnormal
extl3^tm4/tm4	standard conditions	Protruding-mouth	pectoral fin cell circular, abnormal
		Protruding-mouth	pectoral fin fold aplastic, abnormal
		Protruding-mouth	pectoral fin fold distal region aplastic, abnormal
extl3^tm70g/tm70g	standard conditions	Protruding-mouth	pectoral fin cell circular, abnormal
		Protruding-mouth	pectoral fin fold aplastic, abnormal
		Protruding-mouth	pectoral fin fold distal region aplastic, abnormal
extl3^to232/to232	standard conditions	Protruding-mouth	pectoral fin cell circular, abnormal
		Protruding-mouth	pectoral fin fold aplastic, abnormal
		Protruding-mouth	pectoral fin fold distal region aplastic, abnormal
extl3^tp67z/tp67z	standard conditions	Protruding-mouth	pectoral fin cell circular, abnormal
		Protruding-mouth	pectoral fin fold aplastic, abnormal
		Protruding-mouth	pectoral fin fold distal region aplastic, abnormal
extl3^tw24/tw24	standard conditions	Protruding-mouth	pectoral fin cell circular, abnormal
		Protruding-mouth	pectoral fin fold aplastic, abnormal
		Protruding-mouth	pectoral fin fold distal region aplastic, abnormal
fras1^{te262d/te262d}	standard conditions	Prim-5	median fin fold edematous, abnormal
fras1^tj16/tj16	standard conditions	Prim-5	median fin fold edematous, abnormal
fras1^tm95b/tm95b	standard conditions	Prim-5	median fin fold edematous, abnormal
fras1^tr274/tr274	standard conditions	Prim-5	median fin fold edematous, abnormal
frem1a^{tb233b/tb233b}	standard conditions	Long-pec	median fin fold cell circular, abnormal
		Long-pec	median fin fold rough, abnormal
frem1a^tc228/tc228	standard conditions	Long-pec	median fin fold cell circular, abnormal
		Long-pec	median fin fold rough, abnormal
frem1a^{tc280b/tc280b}	standard conditions	Long-pec	median fin fold cell circular, abnormal
		Long-pec	median fin fold rough, abnormal
frem1a^te217/te217	standard conditions	Long-pec	median fin fold cell circular, abnormal
		Long-pec	median fin fold rough, abnormal
frem1a^{te370b/te370b}	standard conditions	Long-pec	median fin fold cell circular, abnormal
		Long-pec	median fin fold rough, abnormal
frem1a^{tg308b/tg308b}	standard conditions	Long-pec	median fin fold cell circular, abnormal
		Long-pec	median fin fold rough, abnormal
frem1a^{tm235b/tm235b}	standard conditions	Long-pec	median fin fold cell circular, abnormal
		Long-pec	median fin fold rough, abnormal
frem1a^tp66/tp66	standard conditions	Long-pec	median fin fold cell circular, abnormal
		Long-pec	median fin fold rough, abnormal
frem1a^{tq266c/tq266c}	standard conditions	Long-pec	median fin fold cell circular, abnormal
		Long-pec	median fin fold rough, abnormal
frem1a^tr240/tr240	standard conditions	Long-pec	median fin fold cell circular, abnormal
		Long-pec	median fin fold rough, abnormal
frem1a^tz245/tz245	standard conditions	Long-pec	median fin fold cell circular, abnormal
		Long-pec	median fin fold rough, abnormal
frem2a^ta90/ta90	standard conditions	Prim-5	median fin fold edematous, abnormal
frem2a^ta90	standard conditions	Prim-5	median fin fold epidermis morphology, abnormal
ham^{te296c/te296c}	standard conditions	Prim-15 - Adult	pectoral fin decreased size, abnormal
		Prim-15 - Adult	pharyngeal arch 3-7 decreased size, abnormal
ham^to16/to16	standard conditions	Prim-15 - Adult	pectoral fin decreased size, abnormal
		Prim-15 - Adult	pharyngeal arch 3-7 decreased size, abnormal
hen^{tq251f/tq251f}	standard conditions	Prim-15 - Adult	pectoral fin decreased size, abnormal
		Prim-15 - Adult	pharyngeal arch 2 skeleton morphology, abnormal
		Prim-15 - Adult	pharyngeal arch 3-7 decreased size, abnormal
hen^{tt209b/tt209b}	standard conditions	Prim-15 - Adult	pectoral fin decreased size, abnormal
		Prim-15 - Adult	pharyngeal arch 3-7 decreased size, abnormal
hen^tu248/tu248	standard conditions	Prim-15 - Adult	pectoral fin decreased size, abnormal
		Prim-15 - Adult	pharyngeal arch 3-7 decreased size, abnormal
hhip^{tc256d/tc256d}	standard conditions	26+ somites - Day 5	median fin fold epithelium undulate, abnormal
		Adult	anal fin aplastic, abnormal
		Adult	lepidotrichium increased amount, abnormal
		Adult	pectoral fin increased size, abnormal
		Adult	ventral fin fold epithelium undulate, abnormal
		Adult	whole organism decreased size, abnormal
hmcn1^ta84/ta84	standard conditions	Prim-5	median fin fold edematous, abnormal
hmcn1^tb22/tb22	standard conditions	Prim-5	median fin fold edematous, abnormal
hmcn1^tc8/tc8	standard conditions	Prim-5	median fin fold edematous, abnormal
hmcn1^te335/te335	standard conditions	Prim-5	median fin fold edematous, abnormal
hmcn1^{tg254b/tg254b}	standard conditions	Prim-5	median fin fold edematous, abnormal
hmcn1^{tj258a/tj258a}	standard conditions	Prim-5	median fin fold edematous, abnormal
hmcn1^{tl246a/tl246a}	standard conditions	Prim-5	median fin fold edematous, abnormal
hmcn1^tl28b/tl28b	standard conditions	Prim-5	median fin fold edematous, abnormal
hmcn1^{tm147c/tm147c}	standard conditions	Prim-5	median fin fold edematous, abnormal
hmcn1^tm42b/tm42b	standard conditions	Prim-5	median fin fold edematous, abnormal
hmcn1^tm51/tm51	standard conditions	Prim-5	median fin fold edematous, abnormal
hmcn1^tm68/tm68	standard conditions	Prim-5	median fin fold edematous, abnormal
hmcn1^tn210/tn210	standard conditions	Prim-5	median fin fold edematous, abnormal
hmcn1^tn3/tn3	standard conditions	Prim-5	median fin fold edematous, abnormal
hmcn1^tp41a/tp41a	standard conditions	Prim-5	median fin fold edematous, abnormal
hmcn1^tq207/tq207	standard conditions	Prim-5	median fin fold edematous, abnormal
hmcn1^tq274/tq274	standard conditions	Prim-5	median fin fold edematous, abnormal
hmcn1^tr3/tr3	standard conditions	Prim-5	median fin fold edematous, abnormal
hmcn1^tt231/tt231	standard conditions	Prim-5	median fin fold edematous, abnormal
hmcn1^tu27a/tu27a	standard conditions	Prim-5	median fin fold edematous, abnormal
hmcn1^{tw234b/tw234b}	standard conditions	Prim-5	median fin fold edematous, abnormal
hmcn1^{ty124b/ty124b}	standard conditions	Prim-5	median fin fold edematous, abnormal
hmcn1^ty58/ty58	standard conditions	Prim-5	median fin fold edematous, abnormal
itga3b^tj2b/tj2b	standard conditions	Long-pec	median fin fold cell circular, abnormal
		Long-pec	median fin fold rough, abnormal
kcnk5b^ty86d/+	standard conditions	Adult	lepidotrichium increased length, abnormal
		Adult	lepidotrichium structure, abnormal
krm^{tc227d/tc227d}	standard conditions	Adult	pectoral fin lepidotrichium absent, abnormal
		Adult	pelvic fin lepidotrichium absent, abnormal
lama5^tc17/tc17	standard conditions	Prim-5	median fin fold edematous, abnormal
lama5^{tk219a/tk219a}	standard conditions	Prim-5	median fin fold edematous, abnormal
lama5^tm55/tm55	standard conditions	Prim-5	median fin fold edematous, abnormal
llgl2^to6/to6	standard conditions	Protruding-mouth - Days 21-29	whole organism dead, abnormal
lof^dt2/+	standard conditions	Adult	lepidotrichium increased length, abnormal
myo5b^tk34a/tk34a	standard conditions	Days 14-20	fin decreased size, abnormal
		Days 14-20	whole organism dead, abnormal
myo5b^tk38/tk38	standard conditions	Days 14-20	whole organism dead, abnormal
myo5b^tt221/tt221	standard conditions	Days 14-20	fin decreased size, abnormal
		Days 14-20	whole organism dead, abnormal
pek^td14/td14	standard conditions	Prim-15 - Adult	pectoral fin decreased size, abnormal
		Prim-15 - Adult	pharyngeal arch 3-7 decreased size, abnormal
		Prim-15 - Adult	whole organism viability, abnormal
prdm1a^tp39/tp39	standard conditions	26+ somites - Day 5	median fin fold decreased length, abnormal
		26+ somites - Day 5	median fin fold deformed, abnormal
		26+ somites - Day 5	median fin fold increased thickness, abnormal
ptch1^tj222/tj222	standard conditions	26+ somites - Day 5	median fin fold epithelium undulate, abnormal
		Adult	whole organism decreased size, abnormal
ptch1^tq236/tq236	standard conditions	26+ somites - Day 5	median fin fold epithelium undulate, abnormal
		Adult	whole organism decreased size, abnormal
smad5^dti216c/+	standard conditions	26+ somites - Day 5	post-vent region kinked, abnormal
		26+ somites - Day 5	post-vent region shortened, abnormal
		26+ somites - Day 5	ventral fin fold hypoplastic, abnormal
		26+ somites - Day 5	whole organism viability, abnormal
smad5^dty40/+	standard conditions	26+ somites - Day 5	ventral fin fold hypoplastic, abnormal
smad5^ta206/ta206	standard conditions	26+ somites - Day 5	pharyngeal arch 3-7 skeleton morphology, abnormal
		26+ somites - Day 5	somite morphology, abnormal
		26+ somites - Day 5	ventral fin fold hypoplastic, abnormal
		26+ somites - Day 5	whole organism viability, abnormal
smad5^{tc227a/tc227a}	standard conditions	26+ somites - Day 5	caudal vein plexus aplastic, abnormal
		26+ somites - Day 5	ventral fin fold hypoplastic, abnormal
smad5^tx223/tx223	standard conditions	26+ somites - Day 5	ventral fin fold hypoplastic, abnormal
		26+ somites - Day 5	whole organism viability, abnormal
sox9a^tw37/tw37	standard conditions	Prim-15 - Adult	pectoral fin decreased size, abnormal
		Prim-15 - Adult	pharyngeal arch 3-7 decreased size, abnormal
sto^td11/td11	standard conditions	Prim-15 - Adult	pectoral fin epithelium degenerate, abnormal
sufu^{tm146d/tm146d}	standard conditions	26+ somites - Day 5	median fin fold epithelium undulate, abnormal
		Adult	anal fin aplastic, abnormal
		Adult	whole organism decreased size, abnormal
szl^tm305/tm305	standard conditions	26+ somites - Day 5	ventral fin fold duplicated, abnormal
		Adult	anal fin duplicated, abnormal
		Adult	caudal fin duplicated, abnormal
szl^tz209/tz209	standard conditions	26+ somites - Day 5	ventral fin fold duplicated, abnormal
		Adult	anal fin duplicated, abnormal
		Adult	caudal fin duplicated, abnormal
tll1^{tc263a/tc263a}	standard conditions	26+ somites - Day 5	ventral fin fold hypoplastic, abnormal
tll1^{tf215a/tf215a}	standard conditions	Bud - Day 5	gastrulation with mouth forming second disrupted, abnormal
		Bud - Day 5	ventral fin fold hypoplastic, abnormal
		Bud - Day 5	whole organism viability, abnormal
tll1^{tm124a/tm124a}	standard conditions	26+ somites - Day 5	ventral fin fold hypoplastic, abnormal
tll1^{tn217b/tn217b}	standard conditions	26+ somites - Day 5	ventral fin fold hypoplastic, abnormal
		26+ somites - Day 5	whole organism viability, abnormal
tll1^{tt203a/tt203a}	standard conditions	26+ somites - Day 5	ventral fin fold hypoplastic, abnormal
		26+ somites - Day 5	whole organism viability, abnormal
tll1^tv9b/tv9b	standard conditions	Bud	gastrulation with mouth forming second disrupted, abnormal
		26+ somites - Day 5	ventral fin fold hypoplastic, abnormal
		26+ somites - Day 5	whole organism viability, abnormal
tll1^{ty130a/ty130a}	standard conditions	Bud	gastrulation with mouth forming second disrupted, abnormal
		26+ somites - Day 5	post-vent region morphology, abnormal
		26+ somites - Day 5	ventral fin fold hypoplastic, abnormal
		26+ somites - Day 5	whole organism viability, abnormal
trim33^{tb222b/tb222b}	standard conditions	26+ somites - Day 5	median fin fold edge shape, abnormal
trim33^{tc239b/tc239b}	standard conditions	26+ somites - Day 5	median fin fold edge shape, abnormal
trim33^{tc246b/tc246b}	standard conditions	26+ somites - Day 5	median fin fold edge shape, abnormal
		26+ somites - Day 5	musculoskeletal movement disrupted, abnormal
		26+ somites - Day 5	trunk musculature morphology, abnormal
		26+ somites - Day 5	whole organism viability, abnormal
trim33^te345/te345	standard conditions	26+ somites - Day 5	median fin fold edge shape, abnormal
		26+ somites - Day 5	musculoskeletal movement disrupted, abnormal
		26+ somites - Day 5	trunk musculature morphology, abnormal
		26+ somites - Day 5	whole organism viability, abnormal
trim33^tg234/tg234	standard conditions	26+ somites - Day 5	median fin fold edge shape, abnormal
trim33^{tu244b/tu244b}	standard conditions	26+ somites - Day 5	median fin fold edge shape, abnormal
		26+ somites - Day 5	musculoskeletal movement disrupted, abnormal
		26+ somites - Day 5	trunk musculature morphology, abnormal
		26+ somites - Day 5	whole organism viability, abnormal
trim33^ty57/ty57	standard conditions	26+ somites - Day 5	median fin fold edge shape, abnormal
		26+ somites - Day 5	musculoskeletal movement disrupted, abnormal
		26+ somites - Day 5	trunk musculature morphology, abnormal
		26+ somites - Day 5	whole organism viability, abnormal
trim33^tz276/tz276	standard conditions	26+ somites - Day 5	median fin fold edge shape, abnormal
tut^tg30/tg30	standard conditions	26+ somites - Day 5	median fin fold hypoplastic, abnormal
		26+ somites - Day 5	median fin fold perforate, abnormal

Acknowledgments:
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