ZFIN Figure: Wiweger et al., 2012, Fig. 4

ZFIN ID: ZDB-FIG-120206-10

ZFIN ID: ZDB-FIG-120206-10

Wiweger et al., 2012 - HSPG-Deficient Zebrafish Uncovers Dental Aspect of Multiple Osteochondromas. PLoS One 7(1):e29734 Full text @ PLoS One

ADDITIONAL FIGURES

PHENOTYPE:

Fish:	ext2^{to273b/to273b} extl3^tw24/tw24 gli1^{tm276b/tm276b} gli2a^ty119/ty119 prkci^m129/m129 slc35b2^{to14mx/to14mx}
Observed In:	ceratobranchial 5 bone ceratobranchial 5 tooth ossification tooth mineralization
Stage:	Day 6

Fig. 4

Tooth phenotype in zebrafish mutants affected in FGF, IHH and PKC pathways.

Pharyngeal arch together with teeth from 6-days-old WT and dackel (dak/ext2), detour (dtr/gli1), heart and soul (has/prkci), pinscher (pic/slc35b2) and you too (yot/gli2a) homozygote mutants were stained with alizarin red, dissected and flat mounted. The average length of the 5^th arch in WT larvae is 150 μm.

Gene Expression Details No data available

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
ext2^{to273b/to273b}	standard conditions	Day 6	ceratobranchial 5 bone decreased length, abnormal
		Day 6	ceratobranchial 5 bone has fewer parts of type ceratobranchial 5 tooth, abnormal
		Day 6	ceratobranchial 5 tooth decreased length, abnormal
		Day 6	ceratobranchial 5 tooth increased thickness, abnormal
extl3^tw24/tw24	standard conditions	Day 6	ceratobranchial 5 bone decreased length, abnormal
		Day 6	ceratobranchial 5 bone has fewer parts of type ceratobranchial 5 tooth, abnormal
		Day 6	tooth mineralization delayed, abnormal
gli1^{tm276b/tm276b}	standard conditions	Day 6	ceratobranchial 5 bone decreased length, abnormal
		Day 6	ceratobranchial 5 bone has fewer parts of type ceratobranchial 5 tooth, abnormal
gli2a^ty119/ty119	standard conditions	Day 6	ceratobranchial 5 bone decreased length, abnormal
		Day 6	ceratobranchial 5 bone has fewer parts of type ceratobranchial 5 tooth, abnormal
		Day 6	ceratobranchial 5 tooth decreased length, abnormal
		Day 6	ceratobranchial 5 tooth increased width, abnormal
prkci^m129/m129	standard conditions	Day 6	ceratobranchial 5 bone decreased length, abnormal
		Day 6	ceratobranchial 5 bone has fewer parts of type ceratobranchial 5 tooth, abnormal
slc35b2^{to14mx/to14mx}	standard conditions	Day 6	ceratobranchial 5 bone decreased length, abnormal
		Day 6	ceratobranchial 5 bone has fewer parts of type ceratobranchial 5 tooth, abnormal
		Day 6	ossification delayed, abnormal
		Day 6	tooth mineralization delayed, abnormal

Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One