ZFIN Figure: Lee et al., 2004, Fig. 5

ZFIN ID: ZDB-FIG-050126-1

ZFIN ID: ZDB-FIG-050126-1

Lee et al., 2004 - Axon Sorting in the Optic Tract Requires HSPG Synthesis by ext2 (dackel) and extl3 (boxer). Neuron 44(6):947-960 Full text @ Neuron

ADDITIONAL FIGURES

EXPRESSION / LABELING:

Genes:	ext2 extl3
Fish:	WT
Anatomical Terms:	nervous system pectoral fin musculature whole organism
Stage Range:	4-cell to Long-pec

PHENOTYPE:

Fish:	ext2^{to273b/to273b} extl3^tm70g/tm70g
Observed In:	retinal ganglion cell axon retinal ganglion cell axon guidance
Stage Range:	Pec-fin to Day 5

Fig. 5 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details

Gene	Fish	Conditions	Stage	Anatomy	Assay
ext2	WT	standard conditions	4-cell	whole organism	ISH
			10-13 somites	whole organism	ISH
			Prim-25	nervous system	ISH
			Prim-25	pectoral fin musculature	ISH
extl3	WT	standard conditions	4-cell	whole organism	ISH
			50%-epiboly	whole organism	ISH
			5-9 somites	whole organism	ISH
			Prim-5	nervous system	ISH
			Long-pec	nervous system	ISH
			Long-pec	pectoral fin musculature	ISH

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
ext2^{to273b/to273b}	standard conditions	Pec-fin - Day 5	retinal ganglion cell axon guidance disrupted, abnormal
		Pec-fin - Day 5	retinal ganglion cell axon irregular spatial pattern, abnormal
extl3^tm70g/tm70g	standard conditions	Protruding-mouth - Day 5	retinal ganglion cell axon guidance disrupted, abnormal
		Protruding-mouth - Day 5	retinal ganglion cell axon irregular spatial pattern, abnormal

Full text @ Neuron