ZFIN Figure: Volpi et al., 2017, Fig. 3

ZFIN ID: ZDB-FIG-170616-17

ZFIN ID: ZDB-FIG-170616-17

Volpi et al., 2017 - EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay.. The Journal of experimental medicine 214(3):623-637 Full text @ J. Exp. Med.

EXPRESSION / LABELING:

Gene:	GFP
Fish:	la6Tg extl3^tm70g/tm70g; la6Tg
Anatomical Term:	thymus
Stage:	Day 6

PHENOTYPE:

Fish:	ext2^{to273b/to273b} extl3^tm70g/tm70g ext2^{to273b/to273b}; la6Tg extl3^tm70g/tm70g; la6Tg
Observed In:	pectoral fin thymus thymus development
Stage:	Day 6

Fig. 3 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details

Gene	Antibody	Fish	Conditions	Stage	Anatomy	Assay
GFP		extl3^tm70g/tm70g; la6Tg	standard conditions	Day 6	thymus	IFL
		la6Tg	standard conditions	Day 6	thymus	IFL

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
ext2^{to273b/to273b}	standard conditions	Day 6	pectoral fin decreased size, abnormal
ext2^{to273b/to273b}; la6Tg	standard conditions	Day 6	thymus decreased volume, abnormal
		Day 6	thymus development disrupted, abnormal
extl3^tm70g/tm70g	standard conditions	Day 6	pectoral fin decreased size, abnormal
extl3^tm70g/tm70g; la6Tg	standard conditions	Day 6	thymus decreased volume, abnormal
		Day 6	thymus development disrupted, abnormal
		Day 6	thymus GFP expression decreased amount, abnormal
		Day 6	thymus GFP expression decreased distribution, abnormal

Full text @ J. Exp. Med.