FIGURE

Fig. 7

ID

ZDB-FIG-250602-12

Publication

Gupta et al., 2025 - Mutations in the microexon splicing regulator srrm4 have minor phenotypic effects on zebrafish neural development

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Fig. 7

Srrm4 expression is decreased in atoh1c G0 crispant larvae at 6 dpf. a, b) srrm4 expression in the lobus caudalis. a) Cas9-injected control and (b) atoh1c G0 crispant. c, d) srrm4 expression in the corpus cerebelli. c) Cas9-injected control. d) atoh1c G0 crispant. e) Quantification of srrm4 expression in atoh1c crispant and Cas9-injected control larvae. Each point represents the normalized srrm4 expression level of an individual larva. Student's t-test P = 0.009. Anterior is to the top. Cc, corpus cerebelli; Lc, lobus caudalis. Scale bar = 100 μm.

Expression Data

Gene:	srrm4
Fish:	TL TL + CRISPR1-atoh1c + CRISPR2-atoh1c
Knockdown Reagents:	CRISPR1-atoh1c CRISPR2-atoh1c
Anatomical Terms:	corpus cerebelli medial caudal lobe
Stage:	Day 6

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	TL + CRISPR1-atoh1c + CRISPR2-atoh1c
Knockdown Reagents:	CRISPR1-atoh1c CRISPR2-atoh1c
Observed In:	corpus cerebelli medial caudal lobe
Stage:	Day 6

Phenotype Detail

Acknowledgments

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