FIGURE

Fig. 2

ID

ZDB-FIG-250602-7

Publication

Gupta et al., 2025 - Mutations in the microexon splicing regulator srrm4 have minor phenotypic effects on zebrafish neural development

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Fig. 2

Srrm4 is expressed in proliferating notch1a and differentiated elavl3 neurons during early brain development. a–d) Partial (20 μm depth) maximum intensity projections of srrm4 mRNA expression at 24 and 48 hpf. Dorsal view in (a) and sagittal view in (b) at 24 hpf. Dorsal view in (c) and sagittal view in (d) at 48 hpf. Anterior is to the left. Scale bars = 100 μm. e–e″) Single plane image of Mo of srrm4 co-labeled with notch1a mRNA at 48 hpf. e) srrm4 expression. e′) notch1a expression. e″) srrm4 and notch1a merged images. f–f″) Single plane image of Mo of srrm4 co-labeled with elavl3 mRNA at 48 hpf. f) srrm4 expression. f′) elavl3 expression. f″) srrm4 and elavl3 merged images. Areas of overlap, which appear yellow, indicate presumed co-localization. Scale bars = 50 μm. Cb, cerebellum; Di, diencephalon; Mo, medulla oblongata; Oe, olfactory epithelium; Ot, optic tectum; Te, telencephalon.

Expression Data

Genes:	elavl3 notch1a srrm4
Fish:	TL
Anatomical Terms:	cerebellum diencephalon hindbrain optic tectum primitive olfactory epithelium rhombomere rhombomere anatomical boundary tegmentum telencephalon
Stage Range:	Prim-5 to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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