Publication	Data		Fish	Anatomy
Fatás-Lalana et al., 2022	Fig. 6		spint1ahi2217Tg/hi2217Tg; nz50Tg	keratinocyte mislocalised, abnormal neutrophil mislocalised, abnormal
	Fig. 7		spint1ahi2217Tg/hi2217Tg; nz50Tg	keratinocyte mislocalised, abnormal neutrophil mislocalised, abnormal
Martínez-Morcillo et al., 2021	Fig 2		spint1ahi2217Tg/hi2217Tg; nz50Tg/nz50Tg ,   spint1ahi2217Tg/hi2217Tg	caudal hematopoietic tissue neutrophil increased amount, abnormal integument hydrogen peroxide biosynthetic process increased occurrence, abnormal keratinocyte cell aggregation increased process quality, abnormal regulation of non-canonical NF-kappaB signal transduction increased process quality, abnormal whole organism NAD biosynthetic process increased process quality, abnormal
	Fig 3		spint1ahi2217Tg/hi2217Tg; nz50Tg/nz50Tg ,   spint1ahi2217Tg/hi2217Tg; nc1Tg/nc1Tg	caudal hematopoietic tissue neutrophil increased amount, abnormal integument hydrogen peroxide biosynthetic process increased occurrence, abnormal
	Fig 4		spint1ahi2217Tg/hi2217Tg; nz50Tg/nz50Tg ,   spint1ahi2217Tg/hi2217Tg; nc1Tg/nc1Tg ,   spint1ahi2217Tg/hi2217Tg	caudal fin regeneration increased process quality, abnormal caudal hematopoietic tissue neutrophil increased amount, abnormal keratinocyte cell division increased process quality, abnormal regulation of non-canonical NF-kappaB signal transduction increased process quality, abnormal
	Fig 5		spint1ahi2217Tg/hi2217Tg; nz50Tg/nz50Tg ,   spint1ahi2217Tg/hi2217Tg	caudal hematopoietic tissue neutrophil increased amount, abnormal keratinocyte caspase complex ab1-casp3 labeling increased amount, abnormal
Armistead et al., 2020	Fig. 1		spint1afr26/fr26 ,   spint1ahi2217Tg/hi2217Tg	caudal fin mmp9 expression increased amount, abnormal caudal fin spint1a expression decreased amount, abnormal caudal fin cell population proliferation increased occurrence, abnormal caudal fin epidermal cell aggregated, abnormal whole organism decreased life span, abnormal
	Fig. 2		spint1ahi2217Tg/hi2217Tg	caudal fin ab1-rps6 labeling increased amount, abnormal caudal fin Ab4-egfr labeling increased amount, abnormal caudal fin cell population proliferation increased occurrence, abnormal caudal fin epidermal cell aggregated, abnormal
	Fig. 3		spint1ahi2217Tg/hi2217Tg; fr46Tg; gz7Tg	epidermal basal stratum cell protruding out of epidermis, abnormal peridermal cell protruding out of epidermis, abnormal
	Fig. 5		WT + MO1-spint1a ,   spint1ahi2217Tg/hi2217Tg	caudal fin mmp9 expression increased amount, abnormal caudal fin epidermal basal stratum ab1-lama1 labeling spatial pattern, abnormal caudal fin epidermal basal stratum structure, abnormal epidermal basal stratum cell protruding out of epidermis, abnormal peridermal cell protruding out of epidermis, abnormal
	Fig. 6		spint1ahi2217Tg/hi2217Tg	caudal fin epidermal cell aggregated, abnormal epidermal basal stratum cell protruding out of epidermis, abnormal peridermal cell protruding out of epidermis, abnormal
	Fig. 7		spint1afr26/fr26	caudal fin cell population proliferation increased occurrence, abnormal epidermal basal stratum cell protruding out of epidermis, abnormal peridermal cell protruding out of epidermis, abnormal whole organism decreased life span, abnormal
Martínez-Navarro et al., 2020	Fig. 3		spint1ahi2217Tg/hi2217Tg; nz50Tg ,   spint1ahi2217Tg/hi2217Tg; nc1Tg ,   spint1ahi2217Tg/hi2217Tg	caudal fin melanocyte increased amount, abnormal integument canonical NF-kappaB signal transduction increased process quality, abnormal integument hydrogen peroxide increased amount, abnormal integument neutrophil increased amount, abnormal
	Fig. 5		spint1ahi2217Tg/hi2217Tg; nz50Tg ,   spint1ahi2217Tg/hi2217Tg; nc1Tg ,   spint1ahi2217Tg/hi2217Tg	caudal fin keratinocyte increased amount, abnormal caudal fin melanocyte increased amount, abnormal integument canonical NF-kappaB signal transduction increased process quality, abnormal integument hydrogen peroxide increased amount, abnormal integument neutrophil increased amount, abnormal
Gómez-Abenza et al., 2019	Fig. 3		spint1ahi2217Tg/hi2217Tg; hzm1Et	caudal fin neoplastic, abnormal
Tyrkalska et al., 2019	Fig. 7		spint1ahi2217Tg/hi2217Tg	cysteine-type endopeptidase activity involved in apoptotic process increased occurrence, abnormal
Schepis et al., 2018	Fig. 2		WT + MO1-spint1a	integument cell aggregated, abnormal
	Fig. 3		cy22Tg + MO1-spint1a ,   spint1ahi2217Tg/hi2217Tg; cy22Tg	epithelial cell protruding out of epidermal superficial stratum, abnormal
	Fig. 4		la213Tg; mu271Tg + MO1-spint1a	epidermal basal stratum cell motility increased occurrence, abnormal epidermal basal stratum cell-cell adhesion decreased process quality, abnormal
	Fig. 5		cy34Tg + MO1-spint1a	epidermal basal stratum cytoplasm ab2-cdh1 labeling mislocalised, abnormal
	Fig. 6		cy34Tg + MO1-spint1a	epidermal basal stratum cell motility increased occurrence, abnormal epidermal superficial stratum cell population proliferation increased occurrence, abnormal
	Fig. 7		la213Tg; mu271Tg + MO1-spint1a ,   cy34Tg + MO1-spint1a ,   WT + MO1-spint1a ,   spint1ahi2217Tg/hi2217Tg	epidermal basal stratum cell population proliferation increased occurrence, abnormal epidermal basal stratum cell-cell adhesion decreased process quality, abnormal epidermal superficial stratum cell population proliferation increased occurrence, abnormal epithelial cell protruding out of epidermal superficial stratum, abnormal whole organism il1b expression increased amount, abnormal whole organism mmp13a expression increased amount, abnormal whole organism mmp9 expression increased amount, abnormal
	Fig. 8		la213Tg; mu271Tg + MO1-spint1a ,   cy34Tg + MO1-spint1a	epidermal basal stratum cell population proliferation increased occurrence, abnormal epidermal basal stratum cell-cell adhesion decreased process quality, abnormal epidermal superficial stratum cell population proliferation increased occurrence, abnormal epithelial cell protruding out of epidermal superficial stratum, abnormal
LeBert et al., 2015	Fig. 1		WT + MO2-spint1a ,   spint1ahi2217Tg/hi2217Tg	epithelium development process quality, abnormal epithelium protruding, abnormal
	Fig. 2		WT + MO2-spint1a	epithelium development process quality, abnormal epithelium neutrophil increased amount, abnormal epithelium protruding, abnormal
	Fig. 3		WT + MO2-spint1a	caudal fin collagen network disorganized, abnormal
Carney et al., 2007	Fig. 1		spint1ahi2217Tg/hi2217Tg	chorion accumulation keratinocyte, abnormal epidermal basal stratum keratinocyte aggregated, abnormal epidermis development disrupted, abnormal keratinocyte mislocalised, abnormal
	Fig. 3		WT + MO1-spint1a ,   spint1ahi2217Tg/hi2217Tg	chorion accumulation keratinocyte, abnormal epidermal basal stratum keratinocyte aggregated, abnormal epidermis development disrupted, abnormal keratinocyte mislocalised, abnormal
	Fig. 5		WT + MO1-spint1a	keratinocyte disorganized, abnormal
	Fig. 6		spint1ahi2217Tg/hi2217Tg	epidermis development disrupted, abnormal leukocyte aggregated, abnormal neutrophil increased amount, abnormal
	Fig. 8		spint1ahi2217Tg/hi2217Tg	epidermis aggregated, abnormal epidermis development disrupted, abnormal
	Fig. S1		spint1ahi2217Tg/hi2217Tg	epidermis development disrupted, abnormal olfactory epithelium morphology, abnormal
Mathias et al., 2007	Fig. 1		spint1ahi2217Tg/hi2217Tg (AB)	epidermis development disrupted, abnormal epidermis disorganized, abnormal epidermis increased thickness, abnormal extension degenerate, abnormal neutrophil mislocalised, abnormal
	Fig. 2		spint1ahi2217Tg/hi2217Tg (AB)	median fin fold morphology, abnormal neutrophil mislocalised, abnormal
	Fig. 3		spint1ahi2217Tg/hi2217Tg (AB)	cell population proliferation increased rate, abnormal macrophage mislocalised, abnormal median fin fold decreased thickness, abnormal median fin fold degenerate, abnormal neutrophil mislocalised, abnormal
	Fig. 4		spint1ahi2217Tg/hi2217Tg (AB)	cell population proliferation increased rate, abnormal epidermis development disrupted, abnormal epidermis disorganized, abnormal extension degenerate, abnormal median fin fold degenerate, abnormal
	Fig. 5		AB + MO2-spint1a	epidermis development disrupted, abnormal epidermis disorganized, abnormal extension degenerate, abnormal median fin fold decreased thickness, abnormal median fin fold degenerate, abnormal median fin fold morphology, abnormal neutrophil mislocalised, abnormal
	Fig. 8		spint1ahi2217Tg/hi2217Tg; uwm1Tg (AB)	neutrophil chemotaxis disrupted, abnormal neutrophil chemotaxis increased rate, abnormal
	Fig. S1		spint1ahi2217Tg/hi2217Tg (AB)	median fin fold morphology, abnormal
Phenotype Annotation (1994-2006)	Fig. for (hi2217)		spint1ahi2217Tg	surface structure quality, abnormal
Amsterdam et al., 2004	text only		spint1ahi2217Tg/hi2217Tg	eye decreased distance eye, abnormal eye decreased size, abnormal fin decreased size, abnormal fin rough, abnormal head decreased size, abnormal swim bladder inflation disrupted, abnormal trunk decreased size, abnormal