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Phenotype Figure Summary
Marker:
mtm1
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Espinosa
et al.
, 2022
Fig. 6.
mtm1
zf711/zf711
(AB)
skeletal muscle cell perinuclear region of cytoplasm ab1-desm labeling increased amount, abnormal
whole organism ab1-desm labeling increased amount, abnormal
Fig. 7.
mtm1
zf711/zf711
(AB)
skeletal muscle cell cytoplasm Ab1-dnm2 labeling increased amount, abnormal
skeletal muscle cell cytoplasm Ab1-dnm2 labeling spatial pattern, abnormal
whole organism Ab1-dnm2 labeling increased amount, abnormal
Sabha
et al.
, 2016
Fig. 6
mtm1
zf711/zf711
(AB)
liver morphology, abnormal
pectoral fin kinked, abnormal
skeletal muscle T-tubule broken, abnormal
skeletal muscle T-tubule lacks all parts of type skeletal muscle sarcoplasmic reticulum, abnormal
ventral fin fold absent, abnormal
whole organism decreased life span, abnormal
whole organism decreased mobility, abnormal
Fig. S7
mtm1
zf711/zf711
(AB)
ventral fin fold absence due to degeneration, abnormal
Fig. S9
mtm1
zf711/zf711
(AB)
, 
AB + MO3-mtm1
ventral fin fold absent, abnormal
ventral fin fold degenerate, abnormal
Gupta
et al.
, 2013
Fig. 2
AB + MO4-mtm1
skeletal muscle refractivity, abnormal
trunk curved dorsal, abnormal
Fig. 3
AB + MO4-mtm1
muscle cell nucleus displaced to muscle cell central region, abnormal
skeletal muscle myofibril disorganized, abnormal
skeletal muscle sarcomere disorganized, abnormal
Fig. 4
AB + MO4-mtm1
skeletal muscle T-tubule absent, abnormal
skeletal muscle T-tubule disorganized, abnormal
Fig. 7
AB + MO4-mtm1
skeletal muscle refractivity, abnormal
skeletal muscle T-tubule disorganized, abnormal
whole organism decreased length, abnormal
Fig. SMovie S1
AB + MO4-mtm1
locomotory behavior disrupted, abnormal
whole organism decreased mobility, abnormal
text only
AB + MO4-mtm1
hatching decreased occurrence, abnormal
Smith
et al.
, 2013
Fig. 3
WT + MO4-mtm1
muscle morphology, abnormal
Robb
et al.
, 2011
Fig. 4
WT + MO1-mtm1
neuromuscular junction development disrupted, abnormal
text only
WT + MO1-mtm1
locomotory behavior decreased occurrence, abnormal
Dowling
et al.
, 2010
Fig. 3
WT + MO3-mtm1
whole organism decreased length, abnormal
whole organism morphology, abnormal
Fig. 4
WT + MO3-mtm1
skeletal muscle cell morphology, abnormal
Fig. 5
WT + MO3-mtm1
skeletal muscle cell perinuclear region of cytoplasm disorganized, abnormal
skeletal muscle cell sarcoplasmic reticulum morphology, abnormal
skeletal muscle cell T-tubule morphology, abnormal
Dowling
et al.
, 2009
Fig. 1
WT + MO1-mtm1
ball deformed, abnormal
extension decreased size, abnormal
head decreased size, abnormal
post-vent region bent, abnormal
post-vent region decreased length, abnormal
trunk curved dorsal, abnormal
trunk musculature decreased size, abnormal
whole organism malformed, abnormal
Fig. 10
WT + MO1-mtm1
skeletal muscle cell decreased functionality, abnormal
Fig. 2
WT + MO1-mtm1
hatching disrupted, abnormal
musculoskeletal movement, spinal reflex action disrupted, abnormal
thigmotaxis disrupted, abnormal
Fig. 3
WT + MO1-mtm1
skeletal muscle cell nucleus increased size, abnormal
skeletal muscle cell nucleus mislocalised, abnormal
skeletal muscle cell nucleus shape, abnormal
skeletal muscle cell separated from skeletal muscle cell, abnormal
Fig. 4
WT + MO1-mtm1
skeletal muscle cell mitochondrion morphology, abnormal
skeletal muscle cell nucleus increased size, abnormal
skeletal muscle cell nucleus shape, abnormal
skeletal muscle cell perinuclear region of cytoplasm disorganized, abnormal
Fig. 5
WT + MO1-mtm1
skeletal muscle cell hypotrophic, abnormal
Fig. 6
WT + MO1-mtm1
phosphatidylinositol dephosphorylation disrupted, abnormal
Fig. 9
WT + MO1-mtm1
skeletal muscle cell sarcoplasmic reticulum disorganized, abnormal
skeletal muscle cell T-tubule disorganized, abnormal
text only
WT + MO2-mtm1
, 
WT + MO3-mtm1
skeletal muscle cell decreased functionality, abnormal
skeletal muscle cell hypotrophic, abnormal
skeletal muscle cell T-tubule disorganized, abnormal
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