FIGURE
Fig. 10
- ID
- ZDB-FIG-100613-2
- Publication
- Dowling et al., 2009 - Loss of myotubularin function results in T-tubule disorganization in zebrafish and human myotubular myopathy
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Fig. 10
Excitation-Contraction Coupling abnormalities in myotubularin morphants. Excitation-contraction (E–C) coupling. Control morphant myofibers could respond to 15 ms depolarizing current injections to 0 mV from 0 to 30 Hz (average max frequency = 27.0+/-0.9 Hz, N = 5). In contrast, myotubularin morphant muscle progressively failed to contract to stimuli above 10 Hz (average maximum frequency = 11.5+/-1.5 Hz, N = 5, p<0.0001). |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Knockdown Reagent: | |
| Observed In: | |
| Stage: | Protruding-mouth |
Phenotype Detail
Acknowledgments
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Full text @ PLoS Genet.