Publication	Data		Fish	Anatomy
Méjécase et al., 2024	Figure 4		chmru848/ru848 (AB)	retina ddit3 expression increased amount, abnormal retina mcl1a expression increased amount, abnormal retina apoptotic process increased occurrence, abnormal
	Figure 6		chmru848/ru848 (AB)	retina hk2 expression increased amount, abnormal retina pfkma expression decreased amount, abnormal retina pgd expression increased amount, abnormal retina prps1a expression increased amount, abnormal retina prps1b expression increased amount, abnormal
Sarkar et al., 2023	Figure 1		chmru848/ru848 (AB)	whole organism atf4a expression increased amount, abnormal whole organism atf6 expression increased amount, abnormal whole organism cat expression decreased amount, abnormal whole organism hspa5 expression increased amount, abnormal whole organism sod3a expression decreased amount, abnormal whole organism txnb expression increased amount, abnormal
	Figure 3		chmru848/ru848 (AB)	lens decreased size, abnormal retina delaminated, abnormal retinal pigmented epithelium atrophied, abnormal whole organism atf4a expression increased amount, abnormal whole organism atf6 expression amount, ameliorated whole organism atf6 expression increased amount, abnormal whole organism hspa5 expression amount, ameliorated whole organism hspa5 expression increased amount, abnormal
	Figure 4		chmru848/ru848 (AB)	lens decreased size, abnormal retina delaminated, abnormal retinal pigmented epithelium atrophied, abnormal whole organism atf4a expression increased amount, abnormal whole organism atf6 expression increased amount, abnormal whole organism cat expression decreased amount, abnormal whole organism hspa5 expression increased amount, abnormal whole organism sod3a expression decreased amount, abnormal whole organism txnb expression increased amount, abnormal
	Figure 5		chmru848/ru848 (AB)	lens decreased size, abnormal retina delaminated, abnormal retinal pigmented epithelium atrophied, abnormal whole organism cat expression decreased amount, abnormal whole organism sod3a expression decreased amount, abnormal whole organism txnb expression increased amount, abnormal
	Figure 6		chmru848/ru848 (AB)	lens decreased size, abnormal retina delaminated, abnormal retinal pigmented epithelium atrophied, abnormal whole organism cat expression decreased amount, abnormal whole organism sod3a expression decreased amount, abnormal whole organism txnb expression increased amount, abnormal whole organism Melanin decreased amount, abnormal
Toualbi et al., 2023	Figure 3		chmru848/ru848 (AB)	ball present, abnormal eye decreased size, abnormal eye patchy pigmentation, abnormal lens opaque, abnormal pericardium edematous, abnormal retina degenerate, abnormal swim bladder uninflated, abnormal whole organism decreased length, abnormal
	Figure 4		chmru848/ru848 (AB)	retinal rod cell rod photoreceptor outer segment ab5-rho labeling decreased distribution, abnormal
Lima Cunha et al., 2021	Figure 6		chmru848/ru848 (AB)	whole organism 1,2-dipalmitoyl-sn-glycerol decreased amount, abnormal whole organism 1-(1Z-octadecenyl)-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine decreased amount, abnormal whole organism 1-hexadecanoyl-2-(4E,7E,10E,13E,16E,19E-docosahexaenoyl)-sn-glycero-3-phosphocholine decreased amount, abnormal whole organism lysophosphatidylserine O-18:0 increased amount, abnormal whole organism N-(docosanoyl)-hexadecasphing-4-enine-1-phosphocholine decreased amount, abnormal
	Figure 7		chmru848/ru848 (AB)	eye decreased size, abnormal lens blurry, abnormal lens structure, abnormal pericardium edematous, abnormal pleuroperitoneal cavity edematous, abnormal retina degenerate, abnormal retina retina layer formation disrupted, abnormal retinal pigmented epithelium atrophied, abnormal retinal pigmented epithelium hypertrophic, abnormal swim bladder uninflated, abnormal whole organism cholesterol increased amount, abnormal whole organism dead, abnormal whole organism viability, abnormal yolk increased length, abnormal
Song et al., 2017	Fig. 1		chmrk10/rk10 ,   chmrk10/rk10; s843Tg	apoptotic process increased occurrence, abnormal eye decreased pigmentation, abnormal eye decreased size, abnormal intestine cell apoptotic, abnormal intestine decreased length, abnormal intestine malformed, abnormal
Yun et al., 2017	Fig. S1		chmrk10/rk10 (TL)	apoptotic process increased occurrence, abnormal cerebellum apoptotic, abnormal eye apoptotic, abnormal eye morphology, abnormal head morphology, abnormal optic tectum apoptotic, abnormal pharyngeal arch morphology, abnormal swim bladder morphology, abnormal whole organism dead, abnormal whole organism decreased life span, abnormal
	Fig. S12		chmrk10/rk10 (TL)	esophageal epithelium Ab3-egfr labeling decreased amount, abnormal pharyngeal arch Ab3-egfr labeling decreased amount, abnormal
Moosajee et al., 2016	Fig. 3		chmru848/ru848	eye decreased size, abnormal eye increased pigmentation, abnormal eye iridophore decreased amount, abnormal gut edematous, abnormal pericardium edematous, abnormal swim bladder uninflated, abnormal whole organism dead, abnormal whole organism decreased life span, abnormal
	Fig. 4		chmru848/ru848	lens morphology, abnormal retina apoptotic, abnormal retina cytoplasm decreased amount, abnormal retina layer formation disrupted, abnormal retina nucleus condensed, abnormal retinal pigmented epithelium atrophied, abnormal
	Fig. 5		chmru848/ru848	whole organism chm expression decreased amount, abnormal
Bae et al., 2009	Fig. 13		chmrk10/rk10	cerebellum granule cell decreased amount, abnormal cerebellum Purkinje cell decreased amount, abnormal eye degenerate, abnormal
Moosajee et al., 2009	Fig. 1		chmru848/ru848	eye decreased size, abnormal lens decreased size, abnormal lens opaque, abnormal pericardium edematous, abnormal pigmentation increased occurrence, abnormal retinal outer nuclear layer has fewer parts of type photoreceptor cell, abnormal spinal cord curvature, abnormal swim bladder inflation arrested, abnormal trunk edematous, abnormal whole organism decreased length, abnormal yolk increased size, abnormal
	Fig. 2		chmru848/ru848	lens decreased size, abnormal lens opaque, abnormal photoreceptor cell disorganized, abnormal photoreceptor cell morphology, abnormal retina degenerate, abnormal retina layer formation disrupted, abnormal retinal neural layer lacks parts or has fewer parts of type retinal outer plexiform layer, abnormal retinal pigmented epithelium hypertrophic, abnormal retinal pigmented epithelium irregular spatial pattern, abnormal retinal pigmented epithelium mislocalised, abnormal
	Fig. 3		chmru848/ru848	apoptotic process increased occurrence, abnormal retina apoptotic, abnormal retinal ganglion cell apoptotic, abnormal retinal outer nuclear layer apoptotic, abnormal whole organism apoptotic, abnormal
	Fig. 6		chmru848/ru848	protein prenylation disrupted, abnormal
	text only		chmru848/ru848	hatching delayed, abnormal whole organism viability, abnormal
Moosajee et al., 2008	Fig. 6		chmru848/ru848	eye decreased size, abnormal eye degenerate, abnormal eye iridophore decreased amount, abnormal lens decreased size, abnormal lens opaque, abnormal pericardium edematous, abnormal retina layer formation disrupted, abnormal retinal pigmented epithelium hypertrophic, abnormal swim bladder inflation arrested, abnormal
Krock et al., 2007	Fig. 1		chmru848/ru848	retina decreased functionality, abnormal visual perception disrupted, abnormal
	Fig. 2		chmru848/ru848	eye decreased size, abnormal retinal photoreceptor layer disorganized, abnormal retinal pigmented epithelium hypertrophic, abnormal retinal pigmented epithelium irregular thickness, abnormal retinal pigmented epithelium melanosome decreased amount, abnormal
	Fig. 3		chmru848/ru848	melanosome organization disrupted, abnormal photoreceptor outer segment layer disorganized, abnormal pigmented epithelial cell vacuolated, abnormal
Phenotype Annotation (1994-2006)	Fig. for (ru848)		chmru848/ru848	inner ear quality, abnormal iridophore irregular spatial pattern, abnormal neuromuscular process controlling balance quality, abnormal
Starr et al., 2004	Fig. 1		chmru848/ru848	eye decreased size, abnormal eye iridophore decreased amount, abnormal eye iridophore irregular spatial pattern, abnormal eye pigmentation process quality, abnormal lens posterior surface degenerate, abnormal photoreceptor outer segment layer disheveled, abnormal pigmented epithelial cell inclusion body increased amount, abnormal retinal pigmented epithelium disorganized, abnormal retinal pigmented epithelium hypertrophic, abnormal retinal pigmented epithelium pigmented epithelial cell displaced to retinal outer nuclear layer, abnormal swim bladder uninflated, abnormal
	Fig. 2		chmru848/ru848	neuromast decreased amount, abnormal neuromast hair cell kinocilium decreased amount, abnormal neuromast hair cell kinocilium decreased length, abnormal neuromast hair cell lacks parts or has fewer parts of type neuromast hair cell stereocilium bundle, abnormal neuromast hair cell stereocilium decreased amount, abnormal
	Fig. 3		chmru848/ru848	detection of mechanical stimulus involved in sensory perception of sound disrupted, abnormal inner ear hair cell non-functional, abnormal
	Fig. 4		chmru848/ru848	hair cell posterior macula decreased amount, abnormal inner ear hair cell decreased amount, abnormal
	Fig. 6		WT + MO1-chm	neuromast decreased amount, abnormal
	text only		chmru848/ru848 ,   WT + MO1-chm	eye decreased size, abnormal eye degenerate, abnormal eye iridophore decreased amount, abnormal eye iridophore irregular spatial pattern, abnormal neuromast hair cell decreased amount, abnormal neuromuscular process controlling balance process quality, abnormal pericardium edematous, abnormal response to auditory stimulus disrupted, abnormal startle response disrupted, abnormal swimming behavior behavioral quality of a process, abnormal whole organism viability, abnormal