FIGURE

Figure 6

ID

ZDB-FIG-250110-110

Publication

M�j�case et al., 2024 - Oxidative Stress, Inflammation and Altered Glucose Metabolism Contribute to the Retinal Phenotype in the Choroideremia Zebrafish

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Figure 6

PFKM overexpression does not improve activity of the glycolysis pathway or oxidative stress 5 dpf in chm^ru848 zebrafish. Expression of genes involved in the glycolysis pathway (a), in the pentose phosphate oxidative branch (b) and in oxidative stress (c) were analysed using RT-qPCR at 5dpf in zebrafish eyes, from uninjected and injected wt and chm^ru848. Data are expressed as mean ± SEM from n = 3 (with 20 eyes per group). Statistical significance was determined by One-way ANOVA. * p < 0.05; ** p < 0.005; *** p < 0.001; **** p < 0.0001. “●”—wt; “▲”—wt + PFKM; “▼”—chm^ru848; “◆”—chm^ru848 + PFKM.

Expression Data

Genes:	cat gapdh hk2 pfkma pgd prps1a prps1b slc2a1b sod3a txnb
Fish:	AB chm^ru848/ru848 (AB)
Anatomical Term:	retina
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	chm^ru848/ru848 (AB)
Observed In:	retina
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Antioxidants (Basel)