ZFIN is now using GRCz12tu for Genomic Data
Gene
hk2
- ID
- ZDB-GENE-040426-2017
- Name
- hexokinase 2
- Symbol
- hk2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable fructokinase activity and glucokinase activity. Predicted to be involved in several processes, including glucose 6-phosphate metabolic process; glycolytic process; and intracellular glucose homeostasis. Predicted to be located in mitochondrial outer membrane. Predicted to be active in cytosol and mitochondrion. Is expressed in several structures, including alar plate midbrain region; digestive system; hatching gland; musculature system; and nervous system. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human HK2 (hexokinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55926 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | ATPase, nucleotide binding domain | Hexokinase | Hexokinase, binding site | Hexokinase, C-terminal | Hexokinase, N-terminal |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q7ZVL7 | InterPro | 919 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers