Fig. 5

Cellular process enrichment analysis reveals that Mycb and Mych regulate biological processes associated with ribosome biogenesis, protein synthesis, chromosome segregation, and cell cycle. (A-C,F,G) Top 10 enriched biological processes for injury-induced genes in Wt fish (A), Mycb-dependent injury-induced genes (B), Mych-dependent injury-induced genes (C), Mycb-, but not Mych-dependent injury-induced genes (F), and Mych-, but not Mycb-dependent injury-induced genes (G). (D,E) Examples of gene families that are induced in reprogrammed MG and the number of family members that are regulated by Mycb and/or Mych. ars, aminoacyl tRNA synthetases; ccn, cyclin; cdc, cell division cycle; cdk, cyclin-dependent kinase; cenp, centromere protein; ddx, deadbox genes; DNA pol, DNA polymerase; eif eef, eukaryotic translation initiation factors and eukaryotic translation elongation factors; kin, kinetochore; lsu, large ribosomal subunit biogenesis; mcm, minichromosome maintenance; mrpl, mitochondrial ribosomal protein large; mrps, mitochondrial ribosomal protein small; ncap, non-SMC condensing; rep, DNA replication; rpl, ribosomal protein large; rps, ribosomal protein small; ssu, small ribosome subunit biogenesis.