FIGURE

Figure 8

ID

ZDB-FIG-201208-38

Publication

Eufrásio et al., 2020 - In vivo Reporter Assays Uncover Changes in Enhancer Activity Caused by Type 2 Diabetes Associated SNPs

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Figure 8

Theoretical model of the functional domains of seq132. Schematic representation from the three possible sequence versions and the respective associated enhancer activity level: high (A), low (B), and no enhancer activity (C). The gene SLC30A08 is represented in blue. The symbol # represents common variants with no association with type 2 diabetes. The wt and risk alleles are represented in black boxes, the putative repressor in red, and the binding site for PDX1 in green. The dashed line shows interdependence.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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