ZFIN ID: ZDB-FIG-200521-19
O'Connor et al., 2019 - Modulation of Agrin and RhoA Pathways Ameliorates Movement Defects and Synapse Morphology in MYO9A-Depleted Zebrafish. Cells   8(8) Full text @ Cells
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Conditions:
Knockdown Reagents:
Observed In:
Stage: Prim-5

Fig. T1 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + CRISPR1-myo9aa + CRISPR1-myo9ab + CRISPR2-myo9aa + CRISPR2-myo9ab standard conditions Prim-5 horizontal myoseptum neuromuscular junction of skeletal muscle fiber decreased size, abnormal
Prim-5 motor neuron axon decreased length, abnormal
Prim-5 myotome decreased size, abnormal
WT + CRISPR1-myo9aa + CRISPR1-myo9ab + CRISPR2-myo9aa + CRISPR2-myo9ab chemical treatment by environment: fasudil hydrochloride Prim-5 horizontal myoseptum neuromuscular junction of skeletal muscle fiber size, ameliorated
Prim-5 motor neuron axon decreased length, abnormal
Prim-5 myotome size, ameliorated
WT + CRISPR1-myo9aa + CRISPR1-myo9ab + CRISPR2-myo9aa + CRISPR2-myo9ab chemical treatment by injection: peptide Prim-5 horizontal myoseptum neuromuscular junction of skeletal muscle fiber size, ameliorated
Prim-5 motor neuron axon length, ameliorated
Prim-5 myotome decreased size, exacerbated
Acknowledgments:
ZFIN wishes to thank the journal Cells for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Cells