ZFIN ID: ZDB-FIG-200521-16
O'Connor et al., 2019 - Modulation of Agrin and RhoA Pathways Ameliorates Movement Defects and Synapse Morphology in MYO9A-Depleted Zebrafish. Cells   8(8) Full text @ Cells
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Conditions:
Knockdown Reagents:
Observed In:
Stage Range: Prim-5 to Long-pec

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + CRISPR1-myo9aa + CRISPR1-myo9ab + CRISPR2-myo9aa + CRISPR2-myo9ab standard conditions Prim-5 whole organism decreased behavioural activity, abnormal
Prim-5 whole organism movement behavioral quality, abnormal
Long-pec thigmotaxis decreased linear velocity, abnormal
Long-pec whole organism viable, normal
WT + CRISPR1-myo9aa + CRISPR1-myo9ab + CRISPR2-myo9aa + CRISPR2-myo9ab chemical treatment by environment: fasudil hydrochloride Long-pec thigmotaxis process quality, ameliorated
Long-pec whole organism viability, ameliorated
WT + CRISPR1-myo9aa + CRISPR1-myo9ab + CRISPR2-myo9aa + CRISPR2-myo9ab chemical treatment by injection: peptide Prim-5 whole organism behavioural activity, ameliorated
Prim-5 whole organism movement behavioral quality, ameliorated
Long-pec thigmotaxis process quality, ameliorated
Acknowledgments:
ZFIN wishes to thank the journal Cells for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Cells