FIGURE

Fig. 5

ID

ZDB-FIG-180131-30

Publication

Gong et al., 2017 - Insm1a Regulates Motor Neuron Development in Zebrafish

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Fig. 5

Over expressions of nkx6.1 and olig2 rescued the motor neuron defects in insm1a deficient embryos. (A,B). Effects of insm1a knockdown on the expressions of nkx6.1 and olig2 at 19, 24, 36, and 48 hpf. Asterisks indicate significant differences (*P < 0.05). (C) Abnormal Caps in insm1a knockdown zebrafish embryos were restored by co-injection of nkx6.1 or olig2 mRNA. Diagrams of Caps in dash line are displayed near the corresponding confocal image. Scale bar = 50 μm. (D) Quantification of zebrafish embryos with abnormal Cap primary motor neuron. Asterisks indicate significant differences (**P < 0.01).

Expression Data

Genes:	nkx6.1 olig2
Fish:	AB AB + MO5-insm1a
Knockdown Reagent:	MO5-insm1a
Anatomical Term:	whole organism
Stage Range:	20-25 somites to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO5-insm1a
Knockdown Reagent:	MO5-insm1a
Observed In:	CaP motoneuron axon whole organism
Stage Range:	20-25 somites to Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Mol. Neurosci.