Gene

olig2

ID

ZDB-GENE-030131-4013

Name

oligodendrocyte lineage transcription factor 2

Symbol

olig2 Nomenclature History

Previous Names

wu:fc64g09

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Is predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in neuron differentiation and regulation of transcription by RNA polymerase II. Acts upstream of or within nervous system development. Is expressed in several structures, including glioblast; nervous system; neural keel; neural plate; and neural tube. Orthologous to human OLIG2 (oligodendrocyte transcription factor 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

119 figures from 78 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 13 figures from 8 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With olig2 Human Ortholog

No data available

Associated With olig2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Family	IPR032658	Oligodendrocyte transcription factor 2
Homologous_superfamily	IPR036638	Helix-loop-helix DNA-binding domain superfamily