Publication	Data		Fish	Anatomy
Warga et al., 2016	Fig. 6		fbxo5ti245/ti245	cell increased size, abnormal cell polyploid, abnormal mitotic cell cycle disrupted, abnormal mitotic cell cycle lacking processual parts cytokinesis, abnormal
Robu et al., 2012	Fig. 1		WT + MO4-fbxo5	cell cycle process quality, abnormal whole organism cell endopolyploid, abnormal whole organism cell polyploid, abnormal whole organism cell tetraploid, abnormal
	Fig. 2		fbxo5hi2648Tg/hi2648Tg ,   WT + MO4-fbxo5	caudal fin curved ventral, abnormal cell cycle process quality, abnormal cell increased size, abnormal head cell death increased process quality, abnormal head decreased size, abnormal somite deformed, abnormal whole organism cell endopolyploid, abnormal whole organism cell polyploid, abnormal whole organism cell tetraploid, abnormal
	Fig. 3		WT + MO4-fbxo5 + MO4-tp53 ,   WT + MO4-fbxo5	cell cycle process quality, abnormal cell death increased process quality, abnormal cell increased size, abnormal whole organism cell endopolyploid, abnormal whole organism cell polyploid, abnormal whole organism cell tetraploid, abnormal
Riley et al., 2010	Fig. 1		fbxo5x1/x1 ,   fbxo5ti245/ti245	anterior neural tube decreased width, abnormal cell cycle lacking processual parts cytokinesis, abnormal cell division absent, abnormal neural plate increased width, abnormal neuron increased size, abnormal whole organism anterior-posterior axis decreased length, abnormal whole organism deformed, abnormal whole organism nucleus increased size, abnormal
	Fig. 2		fbxo5x1/x1	cell cycle lacking processual parts DNA replication, abnormal cell cycle lacking processual parts mitotic cell cycle, abnormal cell division absent, abnormal
	Fig. 3		fbxo5x1/x1	cell division absent, abnormal
	Fig. 4		fbxo5x1/x1	central nervous system morphogenesis disrupted, abnormal central nervous system neuron decreased amount, abnormal endocrine pancreas decreased size, abnormal epiphysis decreased size, abnormal floor plate cell increased size, abnormal floor plate cell separated from floor plate cell, abnormal forebrain ventral region structure, abnormal hypochord cell increased size, abnormal hypochord cell separated from hypochord cell, abnormal motor neuron decreased amount, abnormal neuron increased size, abnormal pancreas decreased size, abnormal pharyngeal endoderm decreased size, abnormal primary motor neuron decreased amount, abnormal pronephric tubule morphology, abnormal reticular formation structure, abnormal Rohon-Beard neuron decreased amount, abnormal spinal cord interneuron decreased amount, abnormal
	Fig. 5		fbxo5x1/x1	commissural neuron axon guidance disrupted, abnormal hindbrain commissure axon disorganized, abnormal hindbrain dorsal region disorganized, abnormal interneuron axon guidance disrupted, abnormal Mauthner neuron axon decreased amount, abnormal neural crest cell migration disrupted, abnormal neuron microtubule molecular quality, abnormal rhombomere 4 morphogenesis disrupted, abnormal
	Fig. 6		fbxo5x1/x1	anterior macula has fewer parts of type auditory receptor cell, abnormal anterior macula unstratified, abnormal ectodermal placode development disrupted, abnormal olfactory placode decreased size, abnormal optic cup hypoplastic, abnormal otic vesicle decreased size, abnormal posterior lateral line neuromast primordium migration disrupted, abnormal posterior lateral line primordium decreased size, abnormal posterior lateral line primordium mislocalised, abnormal protoneuromast absent, abnormal solid lens vesicle decreased size, abnormal solid lens vesicle protruding out of immature eye, abnormal
	Fig. 7		fbxo5x1/x1	regulation of cell division disrupted, abnormal
	text only		fbxo5x1/x1	neural plate increased width, abnormal
Rhodes et al., 2009	Fig. 1		fbxo5hi2648Tg/hi2648Tg	granulocyte decreased amount, abnormal myeloid cell decreased amount, abnormal myeloid lineage restricted progenitor cell decreased amount, abnormal
	Fig. 2		fbxo5hi2648Tg/hi2648Tg; zdf11Tg	myeloid lineage restricted progenitor cell increased size, abnormal
	Fig. 3		fbxo5hi2648Tg/hi2648Tg	erythroid lineage cell increased variability of size, abnormal eye decreased size, abnormal head decreased size, abnormal nucleate erythrocyte increased size, abnormal trunk curved ventral, abnormal
	Fig. 5		fbxo5hi2648Tg/hi2648Tg; zdf11Tg	cell cycle disrupted, abnormal
	Fig. 7		fbxo5hi2648Tg/hi2648Tg	cell chromosome polyploid, abnormal cell chromosome undivided, abnormal DNA replication disrupted, abnormal
	Fig. 8		fbxo5hi2648Tg/hi2648Tg	apoptotic process increased occurrence, abnormal
Warga et al., 2009	Fig. 5		fbxo5ti245/ti245	macrophage decreased amount, abnormal neutrophil decreased amount, abnormal nucleate erythrocyte decreased amount, abnormal whole organism necrotic, abnormal
Zhang et al., 2008	Fig. 1		fbxo5tiy121/tiy121	mitotic cell cycle arrested, abnormal pericardium edematous, abnormal whole organism decreased length, abnormal whole organism lethal (sensu genetics), abnormal
	Fig. S1		fbxo5tiy121/tiy121	somite specification disrupted, abnormal
Phenotype Annotation (1994-2006)	Fig. for (hi2648)		fbxo5hi2648Tg	brain necrotic, abnormal eye decreased size, abnormal whole organism bent, abnormal
	Fig. for (ti245)		fbxo5ti245/ti245	chordate embryonic development arrested, abnormal multicellular organism development arrested, abnormal pigment cell quality, abnormal post-vent region quality, abnormal whole organism lethal (sensu genetics), abnormal
Amsterdam et al., 2004	text only		fbxo5hi2648Tg/hi2648Tg	brain surface feature shape, abnormal central nervous system necrotic, abnormal extension decreased thickness, abnormal eye decreased size, abnormal eye shape, abnormal head decreased size, abnormal head surface feature shape, abnormal trunk bent, abnormal trunk decreased thickness, abnormal trunk degenerate, abnormal ventricular system structure, cavities, abnormal whole organism viability, abnormal yolk circular, abnormal