FIGURE

Fig. 4

ID

ZDB-FIG-260311-270

Publication

Luo et al., 2025 - General transcription factor IIIAa regulates the transcription of somatic 5S rRNA and influences embryonic organ development in zebrafish

Other Figures

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Fig. 4

Generation and characterization of gtf3aa mutants in zebrafish. A Target site of gtf3aa using CRISPR/Cas9. B Upper panel: Sequencing chromatogram of the gtf3aa gRNA target site in wild-type (WT) zebrafish. Lower panel: Chromatogram of the mutant site in the gtf3aa genome. Insertions are shown in lowercase, and missing bases are denoted by “N” followed by the number of deleted bases in parentheses. C Predicted Gtf3aa protein structures from both WT and MT zebrafish. D Expression levels of gtf3aa mRNA in mutant and wild-type larvae at 3 dpf. E Survival rate of gtf3aa^+/− self-cross larvae. The number of larvae used at each stage is shown at the top of each bar. WT wild type, MT mutant type, aa amino acids, dpf days postfertilization

Expression Data

Gene:	gtf3aa
Fish:	AB gtf3aa^{ihb950/ihb950} (AB)
Anatomical Term:	whole organism
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	gtf3aa^{ihb950/ihb950} (AB)
Observed In:	whole organism
Stage:	Day 6

Phenotype Detail

Acknowledgments

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