FIGURE

Fig. 5

ID

ZDB-FIG-260311-271

Publication

Luo et al., 2025 - General transcription factor IIIAa regulates the transcription of somatic 5S rRNA and influences embryonic organ development in zebrafish

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Fig. 5

gtf3aa mutations disrupt 5S rRNA transcription and ribosome biogenesis. A Expression patterns of somatic 5S rRNA in gtf3aa^−/− and gtf3aa^+/+ larvae from 1–5 dpf. 18S rRNA served as the reference gene in qPCR. B Polysome profiling of gtf3aa^−/− and gtf3aa^+/+ larvae at 3 dpf. C Western blot analysis of Rps6 and Rpl35 protein levels in gtf3aa^−/− and gtf3aa^+/+ larvae at 3 dpf, using β-Actin as a loading control. so_5S rRNA somatic 5S rRNA

Expression Data

Genes:	rpl35 rps6
Fish:	AB gtf3aa^{ihb950/ihb950} (AB)
Anatomical Term:	whole organism
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	gtf3aa^{ihb950/ihb950} (AB)
Observed In:	whole organism whole organism large ribosomal subunit whole organism ribosome whole organism small ribosomal subunit
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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