FIGURE

Fig. 3

ID

ZDB-FIG-250611-54

Publication

Hawkey-Noble et al., 2025 - The P4-phospholipid flippase Atp11a is required for maintenance of eye and ear structure in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

Reduced number of hair cells in the O1 neuromast. (A–C) Nuclear staining of four neuromasts in 5 dpf atp11anl1007 larvae with Yo-Pro-1, demonstrating a decrease in the number of positively stained cells in the O1 neuromast in homozygous and heterozygous mutants compared with wild type. (D) Neuromast hair cell quantification for one otic (O1) and three supraoptic (SO1, SO2 and SO3) neuromasts demonstrates a significant reduction in hair cell number for the O1 neuromast in homozygous and heterozygous mutants. Data are mean±s.e.m. with significance calculated using a one-factor ANOVA with Tukey's post-hoc analysis for multiple comparisons. Wild type, n=15; heterozygous, n=36; homozygous mutant, n=12.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	atp11a^{nfl1007/nfl1007} (AB) atp11a^nfl1007/+ (AB)
Observed In:	otic lateral line neuromast neuromast hair cell supraorbital lateral line neuromast hair cell
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Cell Sci.