FIGURE

Fig. 5

ID

ZDB-FIG-250611-56

Publication

Hawkey-Noble et al., 2025 - The P4-phospholipid flippase Atp11a is required for maintenance of eye and ear structure in zebrafish

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Fig. 5

Ultrastructure analysis of atp11anl1007 mutant photoreceptors. (A–D) Photoreceptors in ultrathin sections show a reduction of outer segments in homozygous mutants when compared to wild-type siblings. (E–H) This phenotype partially resolves when mutant larvae are raised in the dark. Quantification of outer segment number (I), length (J) and mitochondrial number (K) confirm a partial rescue via dark-rearing conditions. Data are mean±s.e.m. ***P<0001, **P<0.001, *P<0.01 (one-factor ANOVA with Tukey’s analysis for multiple comparisons). Wild type light, n=6; mutant light, n=6; wild type dark, n=3; mutant dark, n=3. Larvae are at 6 dpf. Scale bars: 2 µm in F for A,B,E,F; 1 µm in H for C,D,G,H.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	atp11a^{nfl1007/nfl1007} (AB)
Condition:	lighting conditions
Observed In:	eye photoreceptor cell mitochondrion photoreceptor outer segment layer photoreceptor outer segment
Stage:	Day 6

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Cell Sci.