FIGURE

Fig. 4

ID

ZDB-FIG-250602-24

Publication

Tian et al., 2025 - C-mannosyltransferase DPY19L1L-mediated Reissner Fiber formation is critical for zebrafish (Danio rerio) body axis straightening

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Fig. 4

Dpy19l1l−/− mutants lack RF. (A) Confocal images showing the location of RF by immunostaining with SCO-spondin antibody (red) and cilia antibody (green) in control siblings and dpy19l1l−/− mutants at 36 hpf. Nuclei counterstained with DAPI. Yellow arrows indicate intact RF in controls. (B) External phenotypes of dpy19l1l−/− mutants injected with vehicle or dpy19l1l mRNA at 36 hpf. (C) Body axis angles of mutants in (B) quantified with ImageJ (means ± SEM; P values above bars, unpaired t test). (D) Confocal images of the reestablished RF (red) in dpy19l1l mRNA-rescued mutants at 36 hpf. Yellow arrows mark reestablished RF.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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