FIGURE

Fig. 3

ID

ZDB-FIG-250602-23

Publication

Tian et al., 2025 - C-mannosyltransferase DPY19L1L-mediated Reissner Fiber formation is critical for zebrafish (Danio rerio) body axis straightening

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Fig. 3

URP2 injection rescues spinal curvature in dpy19l1l−/− mutants. (A) Schematic of URP2 injection site (cerebral ventricle marked by the blue arrow). (B) External phenotypes of control siblings and URP2-injected dpy19l1l−/− mutants at 3 days postinjection. (C to F) Body axis angles of URP2 injection experiment zebrafish at indicated time points, quantified with ImageJ (bar graphs; means ± SEM; P values above bars, unpaired t test). (G) Survival rate of URP2 injection experiment zebrafish at 10 dpf (means ± SEM). (H) External phenotypes (left) and swim trajectories (right) of URP2 injection experiment zebrafish at 10 dpf. (I) Quantification of swimming distance in (H) (means ± SEM, n = 6; P value above bar).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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