FIGURE

Fig. 2

ID

ZDB-FIG-250602-22

Publication

Tian et al., 2025 - C-mannosyltransferase DPY19L1L-mediated Reissner Fiber formation is critical for zebrafish (Danio rerio) body axis straightening

Other Figures

All Figure Page

Back to All Figure Page

Fig. 2

Urp2 transcription is substantial reduced in dpy19l1l mutants. (A) External phenotypes of control siblings, dpy19l1l−/− mutants, and epinephrine-treated dpy19l1l−/− mutants at 48 hpf. The schematic angle illustrates the quantification method in this study. The blue arrow indicates pericardial edema in epinephrine-treated mutants. (B) Body axis angles from (A) quantified with ImageJ (bar graph; means ± SEM). P values (unpaired t test) are shown above bars. (C) qPCR analysis of pkd2l1, uts2ra, urp1, and urp2 expression in control siblings and dpy19l1l−/− mutants at 36 hpf (means ± SEM, n = 3; number above the bar graph represent the P value). (D) WMISH of pkd2l1, urp1, and urp2 in control siblings and dpy19l1l−/− mutants at 36 hpf. The red arrows highlight diminished urp2 expression.

Expression Data

Genes:	pkd2l1 urp1 urp2 uts2r3
Fish:	AB dpy19l1l^{zf4348/zf4348} (AB)
Anatomical Terms:	floor plate spinal cord region whole organism
Stage:	Prim-25

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	dpy19l1l^{zf4348/zf4348} (AB)
Condition:	chemical treatment by environment: (R)-adrenaline
Observed In:	floor plate spinal cord region post-vent region whole organism
Stage Range:	Prim-25 to Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Sci Adv