FIGURE

Figure 5.

ID
ZDB-FIG-230606-24
Publication
Hamling et al., 2023 - The Nature and Origin of Synaptic Inputs to Vestibulospinal Neurons in the Larval Zebrafish
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Figure 5.

Inhibitory current inputs have ipsilateral and contralateral vestibular sensory origins. A, Control trace from a neuron held at 0 mV shows inhibitory input at rest (top). After ipsilateral (middle) or contralateral (bottom) utricular lesion, some cells experience strong loss of inhibitory currents, while others appear unaffected. B, Distribution of IPSC frequency after ipsilateral or contralateral utricular lesions. Symbols correspond with example neurons in A. Control neurons (n = 5) experienced IPSC frequency from 13.7 to 32.5 Hz. After ipsilateral lesions, 4 of 8 neurons experienced IPSC frequencies <2 SDs below control (under 7.5 Hz, symbols outlined in black). After contralateral lesion, 2 of 6 neurons received IPSCs <7.5 Hz. C, IPSC amplitude is unchanged across control and lesion conditions (mean ± SEM).

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