FIGURE

Figure 4.

ID

ZDB-FIG-230606-23

Publication

Hamling et al., 2023 - The Nature and Origin of Synaptic Inputs to Vestibulospinal Neurons in the Larval Zebrafish

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Figure 4.

High-amplitude spontaneous excitatory inputs originate in the ipsilateral ear. A, Lesion schematic: the utricle (gray circle) was physically removed (red “x”) either ipsilateral or contralateral to the recorded vestibulospinal neuron (black circle, “VS”). B, Example current traces from neurons held at −75 mV from control (top), ipsilateral (middle), and contralateral (bottom) experiments; EPSCs are in color. C, Number of EPSC amplitude bins per cell [median ± interquartile range (IQR) in black] is decreased after ipsilateral, but not contralateral, lesion. Asterisks indicate statistically significant differences (p < 0.05). D, EPSC bin amplitudes (median ± IQR in black) are decreased after ipsilateral, but not contralateral, lesion. E, Frequency of events in EPSC bins (median ± IQR in black) is unchanged after ipsilateral or contralateral lesion compared with control cells. F, EPSC amplitude versus frequency for each bin in control and after ipsilateral/contralateral lesions. High-amplitude bins are lost after ipsilateral lesion.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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