ZFIN ID: ZDB-FIG-200423-53
Gong et al., 2020 - The Requirement of Sox2 for the Spinal Cord Motor Neuron Development of Zebrafish. Frontiers in molecular neuroscience   13:34 Full text @ Front. Mol. Neurosci.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Terms:
Stage Range: Long-pec to Protruding-mouth

Figure 6

The results of transcriptomic profiling in Sox2 mutant and wild-type zebrafish. (A) The Venn chart in the control and Sox2 knockout treatment group. Differently continuous change types are displayed, red/green arrow means a gene up-/down-regulation at the time point. The expression correlation between Sox2 and differentially expressed genes (DEGs) at 32 h (B) and 48 h (C); in the networks, the green node represents down-regulated DEGs and the red node represents up-regulated DEGs; moreover, all the DEGs were classified into different groups based on biological function. (D) Effects of Sox2 deficiency on the expressions of two motor neuron regulation-related genes. Experimental embryos were sampled at 12, 24, and 48 hpf (n = 12). Each bar represents the mean ± SD. Values with *, ** and *** above the bars are significantly different (P < 0.05, P < 0.01 and P < 0.001, respectively).

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP ml2Tg standard conditions Long-pec primary motor neuron IFL
Long-pec spinal cord neuron IFL
Protruding-mouth primary motor neuron IFL
Protruding-mouth spinal cord neuron IFL
sox2zf3399/zf3399; ml2Tg standard conditions Long-pec primary motor neuron IFL
Long-pec spinal cord neuron IFL
Protruding-mouth primary motor neuron IFL
Protruding-mouth spinal cord neuron IFL
Antibody Labeling Details No data available
Phenotype Details No data available
Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Mol. Neurosci.