ZFIN ID: ZDB-FIG-200423-51
Gong et al., 2020 - The Requirement of Sox2 for the Spinal Cord Motor Neuron Development of Zebrafish. Frontiers in molecular neuroscience   13:34 Full text @ Front. Mol. Neurosci.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Knockdown Reagent:
Anatomical Term:
Stage Range: Long-pec to Protruding-mouth
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage Range: Long-pec to Protruding-mouth

Figure 4

Sox2 deficiency suppressed neuronal cell differentiation. (A) Confocal imaging analysis of primary motor neurons in the control group, Sox2 mutant group, and morphant group at 48 and 72 hpf (n = 4). Asterisks indicate undifferentiated neuronal cells. (B) Quantification of the undifferentiated neuronal cell in the three different groups. Each bar represents the mean ± SD. Values with ** and *** above the bars are significantly different (P < 0.01 and P < 0.001, respectively).

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP ml2Tg standard conditions Long-pec spinal cord neuron IFL
Protruding-mouth spinal cord neuron IFL
ml2Tg + MO7-sox2 control Long-pec spinal cord neuron IFL
Protruding-mouth spinal cord neuron IFL
sox2zf3399/zf3399; ml2Tg standard conditions Long-pec spinal cord neuron IFL
Protruding-mouth spinal cord neuron IFL
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
ml2Tg + MO7-sox2 control Long-pec spinal cord neuron differentiation decreased process quality, abnormal
Protruding-mouth spinal cord neuron differentiation decreased process quality, abnormal
sox2zf3399/zf3399; ml2Tg standard conditions Long-pec spinal cord neuron differentiation decreased process quality, abnormal
Protruding-mouth spinal cord neuron differentiation decreased process quality, abnormal
Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Mol. Neurosci.