ZFIN ID: ZDB-FIG-190919-25
Tian et al., 2018 - Deficiency of lrp4 in zebrafish and human LRP4 mutation induce aberrant activation of Jagged-Notch signaling in fin and limb development. Cellular and molecular life sciences : CMLS   76(1):163-178 Full text @ Cell. Mol. Life Sci.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage: Long-pec
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage: Long-pec

Fig. 5 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
apc AB + MO1-lrp4 control Long-pec whole organism RTPCR
dkk1b AB control Long-pec pectoral fin ISH
AB + MO1-lrp4 control Long-pec pectoral fin ISH
Long-pec whole organism RTPCR
fzd2 AB + MO1-lrp4 control Long-pec whole organism RTPCR
her1 AB + MO1-lrp4 control Long-pec whole organism RTPCR
her2 AB + MO1-lrp4 control Long-pec whole organism RTPCR
jag1b AB control Long-pec median fin fold ISH
Long-pec pectoral fin ISH
AB + MO1-lrp4 control Long-pec median fin fold ISH
Long-pec pectoral fin ISH
Long-pec whole organism RTPCR
jag2a AB + MO1-lrp4 control Long-pec whole organism RTPCR
jag2b AB + MO1-lrp4 control Long-pec whole organism RTPCR
lhx1a AB + MO1-lrp4 control Long-pec whole organism RTPCR
lrp6 AB + MO1-lrp4 control Long-pec whole organism RTPCR
notch2 AB + MO1-lrp4 control Long-pec whole organism RTPCR
rspo1 AB + MO1-lrp4 control Long-pec whole organism RTPCR
tcf7 AB + MO1-lrp4 control Long-pec whole organism RTPCR
wnt5b AB control Long-pec pectoral fin ISH
AB + MO1-lrp4 control Long-pec pectoral fin ISH
Long-pec whole organism RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
AB + MO1-lrp4 control Long-pec median fin fold jag1b expression increased amount, abnormal
Long-pec pectoral fin dkk1b expression decreased amount, abnormal
Long-pec pectoral fin jag1b expression increased amount, abnormal
Long-pec pectoral fin wnt5b expression increased amount, abnormal
Long-pec whole organism apc expression decreased amount, abnormal
Long-pec whole organism dkk1b expression decreased amount, abnormal
Long-pec whole organism fzd2 expression increased amount, abnormal
Long-pec whole organism her1 expression increased amount, abnormal
Long-pec whole organism her2 expression increased amount, abnormal
Long-pec whole organism jag1b expression increased amount, abnormal
Long-pec whole organism jag2a expression increased amount, abnormal
Long-pec whole organism jag2b expression increased amount, abnormal
Long-pec whole organism lhx1a expression decreased amount, abnormal
Long-pec whole organism lrp6 expression increased amount, abnormal
Long-pec whole organism notch2 expression increased amount, abnormal
Long-pec whole organism rspo1 expression increased amount, abnormal
Long-pec whole organism tcf7 expression increased amount, abnormal
Long-pec whole organism wnt5b expression increased amount, abnormal
Full text @ Cell. Mol. Life Sci.