lhx1a

ID

ZDB-GENE-980526-347

Name

LIM homeobox 1a

Symbol

lhx1a Nomenclature History

Previous Names

lim1
lim1a (1)
wu:fe25d04
wu:fj36b06

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including embryonic morphogenesis; generation of neurons; and kidney development. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. Is expressed in several structures, including germ ring; mesoderm; nervous system; neural rod; and renal system. Orthologous to human LHX1 (LIM homeobox 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

55 figures from 36 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

eu502 (18 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With lhx1a Human Ortholog

No data available

Associated With lhx1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017970	Homeobox, conserved site
Domain	IPR001356	Homeodomain
Domain	IPR001781	Zinc finger, LIM-type
Domain	IPR049618	Lhx1/5, LIM domain 1
Domain	IPR049619	Lhx1/5, LIM domain 2
Family	IPR050453	LIM/homeobox transcription factors
Homologous_superfamily	IPR009057	Homedomain-like superfamily