FIGURE

Fig. S3

ID

ZDB-FIG-190618-51

Publication

Hanovice et al., 2019 - Regeneration of the zebrafish retinal pigment epithelium after widespread genetic ablation

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Fig. S3

Metronidazole treatment does not cause ONL or RPE apoptosis in nontransgenic larvae.

(A-D) Transverse cryosections stained for TUNEL (red). No TUNEL⁺ cells were detected in nontransgenic larvae (A,C) treated with and without MTZ. (E,F) Quantification of TUNEL⁺cells/section in the ONL (E) and RPE (F). While ONL death appeared to be elevated in unablated rpe65a:nfsB-eGFP⁺ larvae, the increase was not significant (p = 0.1848), and no significant elevation of TUNEL⁺ cells was detected in the RPE (Mann-Whitney U test, *P<0.05, **p<0.005, ***p<0.0005). Scale bar = 40μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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