FIGURE

Fig. 6

ID

ZDB-FIG-161116-14

Publication

Almeida et al., 2016 - Oligodendrocyte Development in the Absence of Their Target Axons In Vivo

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Fig. 6

OPCs are specified normally despite reduction in reticulospinal neurons.

A, Posterior region of 48-60hpf Tg(olig2:EGFP; sox10:mRFP). EGFP+ mRFP+ cells (OPCs) indicated by arrowheads. At 60hpf some OPCs have migrated dorsally. Scale bar: 20 μm. B-C, Similar number of OPCs in 448μm-long regions of the spinal cord between WT and mutants at 48hpf (B) and 60hpf (C). Data from N = 10 WT and N = 9 mutants (48hpf anterior and 60hpf posterior) and N = 18 WT and N = 20 mutants. Error bars indicate ± SD.

Expression Data

Genes:	EGFP mRFP
Fish:	vu12Tg; vu234Tg kifbp^st23/st23; vu12Tg; vu234Tg
Anatomical Terms:	oligodendrocyte cytoplasm oligodendrocyte membrane spinal cord oligodendrocyte
Stage Range:	Long-pec to Pec-fin

Expression Detail

Gene	Fish	Conditions	Stage	Anatomy	Assay
EGFP	kifbp^st23/st23; vu12Tg; vu234Tg	standard conditions	Long-pec	oligodendrocyte cytoplasm	IFL
EGFP	kifbp^st23/st23; vu12Tg; vu234Tg	standard conditions	Long-pec	spinal cord oligodendrocyte	IFL
EGFP	kifbp^st23/st23; vu12Tg; vu234Tg	standard conditions	Pec-fin	oligodendrocyte cytoplasm	IFL
EGFP	kifbp^st23/st23; vu12Tg; vu234Tg	standard conditions	Pec-fin	spinal cord oligodendrocyte	IFL
EGFP	vu12Tg; vu234Tg	standard conditions	Long-pec	oligodendrocyte cytoplasm	IFL
EGFP	vu12Tg; vu234Tg	standard conditions	Long-pec	spinal cord oligodendrocyte	IFL
EGFP	vu12Tg; vu234Tg	standard conditions	Pec-fin	oligodendrocyte cytoplasm	IFL
EGFP	vu12Tg; vu234Tg	standard conditions	Pec-fin	spinal cord oligodendrocyte	IFL
mRFP	kifbp^st23/st23; vu12Tg; vu234Tg	standard conditions	Long-pec	oligodendrocyte membrane	IFL
mRFP	kifbp^st23/st23; vu12Tg; vu234Tg	standard conditions	Long-pec	spinal cord oligodendrocyte	IFL

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Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One