ZFIN Figure: Yeo et al., 2007, Fig. 1

ZFIN ID: ZDB-FIG-070619-5

ZFIN ID: ZDB-FIG-070619-5

Yeo et al., 2007 - Jagged-mediated Notch signaling maintains proliferating neural progenitors and regulates cell diversity in the ventral spinal cord. Proceedings of the National Academy of Sciences of the United States of America 104(14):5913-5918 Full text @ Proc. Natl. Acad. Sci. USA

ADDITIONAL FIGURES

EXPRESSION / LABELING:

Genes:	alcama gad1b isl1a isl2a jag1b jag2b
Fish:	AB AB + MO4-jag1b AB + MO8-jag2b zf532Tg zf532Tg + MO8-jag2b
Knockdown Reagents:	MO4-jag1b MO8-jag2b
Anatomical Terms:	primary motor neuron spinal cord
Stage Range:	Prim-5 to Prim-15

PHENOTYPE:

Fish:	AB + MO4-jag1b AB + MO8-jag2b
Knockdown Reagents:	MO4-jag1b MO8-jag2b
Observed In:	primary motor neuron spinal cord spinal cord GABAergic neuron spinal cord motor neuron
Stage Range:	20-25 somites to Prim-5

Fig. 1 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details

Gene	Fish	Conditions	Stage	Anatomy	Assay
alcama	zf532Tg	control	Prim-5	spinal cord	IHC
			Prim-15	spinal cord	IHC
	zf532Tg + MO8-jag2b	standard conditions	Prim-5	spinal cord	IHC
			Prim-15	spinal cord	IHC
gad1b	AB	control	Prim-5	spinal cord	ISH
	AB + MO4-jag1b	standard conditions	Prim-5	spinal cord	ISH
	AB + MO8-jag2b	standard conditions	Prim-5	spinal cord	ISH
isl1a	AB	control	Prim-5	spinal cord	ISH
	AB + MO4-jag1b	standard conditions	Prim-5	spinal cord	ISH
	AB + MO8-jag2b	standard conditions	Prim-5	spinal cord	ISH
isl2a	AB	control	Prim-5	primary motor neuron	ISH
			Prim-5	spinal cord	ISH
	AB + MO4-jag1b	standard conditions	Prim-5	primary motor neuron	ISH
			Prim-5	spinal cord	ISH
	AB + MO8-jag2b	standard conditions	Prim-5	primary motor neuron	ISH
			Prim-5	spinal cord	ISH
jag1b	AB	standard conditions	Prim-5	spinal cord	ISH
jag2b	AB	standard conditions	Prim-5	spinal cord	ISH

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
AB + MO4-jag1b	standard conditions	20-25 somites - Prim-5	spinal cord has normal numbers of parts of type primary motor neuron, normal
AB + MO8-jag2b	standard conditions	20-25 somites	spinal cord has normal numbers of parts of type primary motor neuron, normal
		Prim-5	spinal cord GABAergic neuron increased amount, abnormal
		Prim-5	spinal cord motor neuron increased amount, abnormal
		Prim-5	spinal cord motor neuron mislocalised, abnormal

Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA