FIGURE

Fig. 6

ID

ZDB-FIG-250609-75

Publication

Eski et al., 2025 - Cholangiocytes contribute to hepatocyte regeneration after partial liver injury during growth spurt in zebrafish

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Fig. 6

her2+ cells generate hepatocytes after PHx.

A The transgenic lines used to lineage trace her2+ cells. B Schematic illustrating the tracing of her2 + -derived hepatocytes following PHx. C Experimental timeline for lineage tracing. D, F Live confocal images of left lobe in uninjured and PHx condition at 4 dpi (D) and at 8 dpi (F). Representative cholangiocyte-derived de novo hepatocytes are marked with arrowheads. Dashed line marks the border of the regenerate. E, G Min-to-max box plots showing the normalized number of H2B-mGL⁺/mCherry⁺ hepatocytes per unit volume at 4 dpi (E) and 8 dpi (G). Each dot represents one animal; mean ± SEM is indicated above each box. Statistical significance was assessed using the Two-tailed Mann–Whitney test. Sample sizes are indicated below the respective groups. Scale bars: 100 μm (left panels), 50 μm (insets) (D, F).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nat. Commun.