FIGURE
Figure 10
- ID
- ZDB-FIG-250329-11
- Publication
- Li et al., 2025 - Identification of Key Active Constituents in Eucommia ulmoides Oliv. Leaves Against Parkinson's Disease and the Alleviative Effects via 4E-BP1 Up-Regulation
- Other Figures
- All Figure Page
- Back to All Figure Page
Figure 10
The proposed mechanism underlying the effect of 30% EF on activating 4E-BP1 under PD conditions. MPTP-induced intracellular alterations lead to a decrease in 4E-BP1 expression, enhancing eIF4F complex formation and potentially facilitating abnormal protein synthesis. In contrast, the application of 30% EF counteracts these effects by up-regulating 4E-BP1, which restores translational homeostasis and cellular damage, ultimately alleviating Parkinsonian symptoms. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ Int. J. Mol. Sci.