FIGURE

Fig. 4.

ID

ZDB-FIG-250122-55

Publication

Willoughby et al., 2024 - Abca4, mutated in Stargardt Disease, is required for cone outer segment structural integrity

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Fig. 4.

Morphology of COS, ROS and RPE in retinas of 1-year-old zebrafish. (A-F) Confocal z-projections of COS, ROS and RPE in retinas obtained from wild-type or abca4a^ca30/ca30, abca4b^ca33/ca33, abca4a^ca30/ca30;abca4b^ca33/ca33 and abca4a^ca31/ca31;abca4b^ca33/ca33 mutant zebrafish. (A) Green COS stained for Green Opsin (green, z=4.3 µm), (B) red COS stained for PNA (red, z=4.3 µm), (C) blue COS stained for Blue Opsin (cyan, z=4.3 µm), (D) UV cones expressing EGFP stained for GFP (violet, z=4.4 µm;), (E) ROS stained for -rhodopsin (white, z=1.9 µm) and (F) RPE expressing tdTomato stained for RFP (white, z=2.4 µm). Nuclei (blue) were labeled with DAPI. Scale bars: 10 µm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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