FIGURE

Fig 6

ID

ZDB-FIG-231208-60

Publication

Michel et al., 2023 - Electrical synapse structure requires distinct isoforms of a postsynaptic scaffold

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Fig 6

Model of tjp1b/ZO1b isoform contribution to electrical synapse assembly.

Diagram summarizing the contribution of each ZO1b isoform to electrical synapse formation in the Mauthner circuit. Unique first exons of tjp1b/ZO1b-Alpha (black), -Beta (magenta), and -Gamma (blue) are denoted by triangles on the tjp1b-ZO1b locus (grey bar) with relative exon structure denoted (dark grey rectangles). Curved arrows indicate unique transcription initiation sites. ZO1b-Beta and -Gamma both localized to the electrical synapse, yet only the ZO1b-Beta isoform is required for robust Connexin (grey ovals) localization to synaptic contacts.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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