FIGURE

Figure 6

ID

ZDB-FIG-230731-101

Publication

Rutkove et al., 2023 - Surface Electrical Impedance Myography Detects Skeletal Muscle Atrophy in Aged Wildtype Zebrafish and Aged gpr27 Knockout Zebrafish

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Figure 6

Genetic deletion of gpr27 exacerbates age-related atrophy of caudal muscle. sEIM parameters were measured at frequencies of 1 kHz–1 MHz in the epaxial caudal muscles of aged sibling WTs (36 months, 85% lifespan, n = 14) and aged gpr27 KOs (36 months, 85% lifespan, n = 14). Multifrequency graphs for (A) phase, (B) reactance, and (C) resistance (n = 14 per genotype). Single frequency analyses at (D) 2 kHz phase (p = 0.0006, q = 0.0012), (E) 2 kHz reactance (p = 0.0011, q = 0.0012), (F) 2 kHz resistance (p = 0.0273, q = 0.0082), (G) 50 kHz phase (p = 0.0229, q = 0.0082), (H) 50 kHz reactance (p = 0.0101, q = 0.0070), (I) 50 kHz resistance, (J) 250 kHz phase (p = 0.0258, q = 0.0082), (K) 250 kHz reactance, (L) 250 kHz resistance (p = 0.0249, q = 0.0082). * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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