FIGURE

Fig. 1

ID
ZDB-FIG-230420-67
Publication
Wang et al., 2023 - Transgenic IDH2R172K and IDH2R140Q zebrafish models recapitulated features of human acute myeloid leukemia
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Fig. 1

Lineage-specific expression of IDH2 mutations exacerbated hematopoiesis and myelopoiesis in zebrafish embryos.

A Brightfield images of WISH for cmyb at 36hpf, mpo at 48hpf, and rag1 at 5dpf in the mutant (n = 20) and WT (n = 20) zebrafish embryos. B Quantification of cmyb, mpo (C), and rag1 (D) respectively. The expression of each marker was presented as the percentage of each marker expressed in the mutant embryos relative to that of the WT embryos. Data are mean ± s.e.m and statistical analysis was performed by One-way Anova, *P < 0.05, **P < 0.01, ****P < 0.0001.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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