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Fig. 1
Lineage-specific expression of IDH2 mutations exacerbated hematopoiesis and myelopoiesis in zebrafish embryos.
A Brightfield images of WISH for cmyb at 36hpf, mpo at 48hpf, and rag1 at 5dpf in the mutant (n = 20) and WT (n = 20) zebrafish embryos. B Quantification of cmyb, mpo (C), and rag1 (D) respectively. The expression of each marker was presented as the percentage of each marker expressed in the mutant embryos relative to that of the WT embryos. Data are mean ± s.e.m and statistical analysis was performed by One-way Anova, *P < 0.05, **P < 0.01, ****P < 0.0001.
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