FIGURE

Fig. 5

ID

ZDB-FIG-230306-34

Publication

Da'as et al., 2023 - The link between glycemic control measures and eye microvascular complications in a clinical cohort of type 2 diabetes with microRNA-223-3p signature

Other Figures

All Figure Page

Back to All Figure Page

Fig. 5

miR-223-3p association with zebrafish eye defects. A the different groups were imaged at ×150 magnification, and the eye images were traced using danioscope software (Noldus Technologies, Netherlands) for eye size measurement. Images were obtained using Lumar 12 stereomicroscope (Zeiss Microscopy) and a Nikon camera at ×100 magnification; scale bar, 10 mm. B incubation of the different groups in glucose affected the development of the eyes, as demonstrated by aberrant vasculature nourishment that led to a significant reduction in eye size. The different groups incubated in 2% and 5% glucose showed significantly reduced eye size on day 3. The miR-223-3p mimic had severely impaired eye morphology compared to the controls in the 5% glucose condition. Total number of larvae measured was n = 10 per group. Statistical analysis was conducted using ANOVA Graph Pad version 9.0

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J Transl Med