FIGURE

Figure 4

ID

ZDB-FIG-220219-91

Publication

Sundaramurthi et al., 2022 - Uveal Melanoma Cell Line Proliferation Is Inhibited by Ricolinostat, a Histone Deacetylase Inhibitor

Other Figures

All Figure Page

Back to All Figure Page

Figure 4

Proteome profiling of ACY-1215-treated cells to uncover mechanism of action. (A): ACY-1215 treatment regime for proteome profiling of OMM2.5 cells. Hours post treatment (hpt). (B): Heat map showing all significant differentially expressed proteins at 24 h post 20 μM ACY-1215 treatment in OMM2.5 cells. A total of 4423 proteins were identified in MS, with 150 downregulated (blue) and 202 upregulated (red) proteins (N = 4). (C,D): Enriched protein pathway analysis for GO term: biological processes for down and upregulated proteins, given a fold change cut off of +/− ≥ 1.2, p ≤ 0.05 displayed as pie charts. *, p < 0.05 and **, p < 0.01 denotes GO-term significance.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cancers