FIGURE

Fig. 2

ID

ZDB-FIG-190821-4

Publication

Xie et al., 2019 - Schwann cell precursors contribute to skeletal formation during embryonic development in mice and zebrafish

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Fig. 2

SCPs generate chondroprogenitors in craniofacial region and trunk during murine embryonic development. Genetic labeling in Plp1^CreERT2;R26R^YFP/+ embryos from E11.5 to E12.5 revealed no overlap between SCPs and SOX9⁺ chondroprogenitors (A and B). Prolonged tracing revealed appearance of SCP progeny in cartilage at E15.5 (C and D) and E17.5 (E and F). Orange arrowheads and white arrows indicate YFP⁺ cells on TUJ1⁺ nerves and close to nerves and cartilage, respectively, and white arrowheads indicate YFP⁺SOX9⁺ chondrocytes in C′ and D′. The orange arrow in E′ indicates an YFP⁺ perichondrial cell. These images represent at least 5 Cre⁺embryos from independent litters. A total of 5 facial and 2 trunk skeletal elements in each embryo were checked

Expression Data

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Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA