ZFIN Image: Xie et al., 2019, Fig. 2

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Figure Caption

Fig. 2

SCPs generate chondroprogenitors in craniofacial region and trunk during murine embryonic development. Genetic labeling in Plp1^CreERT2;R26R^YFP/+ embryos from E11.5 to E12.5 revealed no overlap between SCPs and SOX9⁺ chondroprogenitors (A and B). Prolonged tracing revealed appearance of SCP progeny in cartilage at E15.5 (C and D) and E17.5 (E and F). Orange arrowheads and white arrows indicate YFP⁺ cells on TUJ1⁺ nerves and close to nerves and cartilage, respectively, and white arrowheads indicate YFP⁺SOX9⁺ chondrocytes in C′ and D′. The orange arrow in E′ indicates an YFP⁺ perichondrial cell. These images represent at least 5 Cre⁺embryos from independent litters. A total of 5 facial and 2 trunk skeletal elements in each embryo were checked

Acknowledgments

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