| ZFIN ID: ZDB-FIG-181207-71 |
Teng et al., 2018
- Altered bone growth dynamics prefigure craniosynostosis in a zebrafish model of Saethre-Chotzen syndrome.
eLIFE
7
Full text @ Elife
EXPRESSION / LABELING:
| Antibody: | |
|---|---|
| Fish: | |
| Anatomical Terms: | |
| Stage: | Days 21-29 |
PHENOTYPE:
| Fish: | |
|---|---|
| Observed In: | |
| Stage: | Days 21-29 |
Fig. 5-S2 Additional examples of BrdU and Sp7 staining in tcf12; twist1b mutant zebrafish. Dorsal views of 9 mm zebrafish skullcaps stained with Sp7 antibody (green) and BrdU (magenta) show an array of altered bone shapes in mutants compared to wild type. fb, frontal bone; pb, parietal bone. |
Gene Expression Details
No data available
Antibody Labeling Details
| Antibody | Assay | Fish | Conditions | Stage | Anatomy |
|---|---|---|---|---|---|
| Ab1-sp7 | IHC | b1212Tg | standard conditions | Days 21-29 | cranial vault osteoblast |
| IHC | Days 21-29 | frontal bone osteoblast | |||
| IHC | Days 21-29 | parietal bone osteoblast | |||
| IHC | twist1bel570/el570; tcf12el548/el548; b1212Tg | standard conditions | Days 21-29 | cranial vault osteoblast | |
| IHC | Days 21-29 | frontal bone osteoblast | |||
| IHC | Days 21-29 | parietal bone osteoblast |
Phenotype Details
| Fish | Conditions | Stage | Phenotype |
|---|---|---|---|
| twist1bel570/el570; tcf12el548/el548; b1212Tg | standard conditions | Days 21-29 | frontal bone morphology, abnormal |
| Days 21-29 | parietal bone morphology, abnormal |
| Acknowledgments: | This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Elife |
|---|