FIGURE

Fig. 1-S3

ID
ZDB-FIG-181207-66
Publication
Teng et al., 2018 - Altered bone growth dynamics prefigure craniosynostosis in a zebrafish model of Saethre-Chotzen syndrome
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Fig. 1-S3

Zebrafish skull phenotypes in different mutant combinations.

Dorsal views of adult zebrafish skull bones stained with Alizarin Red. We observed coronal suture loss (asterisks) in tcf12-/-; twist1b-/- mutants of any twist1a genotype (D–F). Animals lacking both Twist1 homologs occasionally develop ectopic sutures (arrows) in the anterior frontal bone region (B,C, enlarged in F). We also occasionally observed gaps (arrowhead, (D) and ectopic sutures (arrows, enlarged in G) in the posterior region of the parietal bone. Scale bars, 1 mm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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