FIGURE

Fig. S5

ID

ZDB-FIG-180827-21

Publication

Ferrero et al., 2018 - Embryonic Microglia Derive from Primitive Macrophages and Are Replaced by cmyb-Dependent Definitive Microglia in Zebrafish

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Fig. S5

The kdrl promoter is not active in adult microglia, related to Figure 3

(A) RT-PCR shows that microglia (MG#1-3) do express apoeb but not kdrl. In contrast, sorted kdrl:GFP+ cells express kdrl but not apoeb.

(B) Immunohistochemistry against GFP and l-plastin performed on adult brain sections dissected from a kdrl:GFP transgenic animal. The vascular marker (GFP) and pan-leukocyte marker (l-plastin) never colocalize, showing that adult microglia do not express kdrl. Scale bar = 25μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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